Anti-SARS spike glycoprotein antibody - C-terminal (ab252690)
Key features and details
- Rabbit polyclonal to SARS spike glycoprotein - C-terminal
- Suitable for: ELISA
- Isotype: IgG
Overview
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Product name
Anti-SARS spike glycoprotein antibody - C-terminal
See all SARS spike glycoprotein primary antibodies -
Description
Rabbit polyclonal to SARS spike glycoprotein - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: ELISAmore details -
Species reactivity
Reacts with: SARS-CoV -
Immunogen
Synthetic peptide corresponding to Human SARS spike glycoprotein (C terminal).
Database link: P59594 -
General notes
Applications overview
Tick: Tested and Guaranteed to work X: Will not work —: No data Reviews: Customers have been successful and shared their AbReview
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab252690 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
ab252690 will detect 10 ng of free peptide at 1 µg/mL. |
| Notes |
|---|
|
ELISA
Use at an assay dependent concentration. ab252690 will detect 10 ng of free peptide at 1 µg/mL. |
Target
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Relevance
A novel coronavirus has been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive stranded RNA approximately 27 to 31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2. -
Alternative names
- E2 antibody
- E2 glycoprotein antibody
- Human coronavirus spike glycoprotein antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (4)
ab252690 has been referenced in 4 publications.
- Wettstein L et al. Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection. Nat Commun 12:1726 (2021). PubMed: 33741941
- Rauch S et al. mRNA-based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus-neutralising antibodies and mediates protection in rodents. NPJ Vaccines 6:57 (2021). PubMed: 33863911
- Ke Z et al. Structures and distributions of SARS-CoV-2 spike proteins on intact virions. Nature 588:498-502 (2020). PubMed: 32805734
- Pellegrini L et al. SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids. Cell Stem Cell 27:951-961.e5 (2020). PubMed: 33113348
