SB 203580 (DMSO solution), p38 MAPK inhibitor (ab146589)

Overview

  • Product name

    SB 203580 (DMSO solution), p38 MAPK inhibitor
  • Description

    p38 MAPK inhibitor
  • Biological description

    Cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1, RIP2, c-Raf and GSK3.

    Also available as a solid (ab120162).
  • Purity

    > 98%
  • CAS Number

    152121-47-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine
  • Molecular weight

    377.43
  • Molecular formula

    C21H16FN3OS
  • PubChem identifier

    176155
  • Storage instructions

    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Supplied in DMSO (10 mM)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CS(=O)c1ccc(cc1)c2nc(c(n2)c3ccncc3)c4ccc(F)cc4
  • Source

    Synthetic

References

ab146589 has not yet been referenced specifically in any publications.

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