Key features and details
- Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor
- CAS Number: 292605-14-2
- Purity: > 98%
- Soluble in DMSO to 25 mM and ethanol
- Form / State: Solid
- Source: Synthetic
Product nameSB-3CT, MMP-2 and MMP-9 inhibitor
DescriptionPotent, competitive and non-selective MMP-2 and MMP-9 inhibitor
Biological descriptionPotent, competitive and non-selective MMP-2 and MMP-9 inhibitor (Ki values are 13.9 and 600 nM for MMP-2 and MMP-9 respectively). Does not alter the activity of MMP-1, MMP-3 or MMP-7 (Ki values are 206 (MMP-1), 15 (MMP-3) and 96 (MMP-7) μM). Neuroprotective and blood-brain barrier permeable.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM and ethanol
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141579 has been referenced in 2 publications.
- Kumar S et al. MMP Secretion Rate and Inter-invadopodia Spacing Collectively Govern Cancer Invasiveness. Biophys J 114:650-662 (2018). PubMed: 29414711
- Rai D et al. Cerebrospinal fluid cytokines and matrix metalloproteinases in human immunodeficiency seropositive and seronegative patients of tuberculous meningitis. Ann Indian Acad Neurol 17:171-8 (2014). PubMed: 25024567