SC-1 (Pluripotin), Dual kinase and GTPase inhibitor (ab144425)

Overview

  • Product name

    SC-1 (Pluripotin), Dual kinase and GTPase inhibitor
  • Description

    Dual kinase (ERK1, MAPK3) and GTPase inhibitor
  • Biological description

    Dual kinase (ERK1, MAPK3) and GTPase inhibitor. Activates stem cell renewal. Enables propagation of undifferentiated murine ESCs in the absence of leukemia inhibitory factor.
  • Purity

    > 98%
  • CAS Number

    839707-37-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mertins SD  et al. A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept. PLoS One 8:e57099 (2013). Read more (PubMed: 23437320) »
  • Al-Habib M  et al. Small molecules affect human dental pulp stem cell properties via multiple signaling pathways. Stem Cells Dev 22:2402-13 (2013). Read more (PubMed: 23573877) »
  • Yang W  et al. Pluripotin combined with leukemia inhibitory factor greatly promotes the derivation of embryonic stem cell lines from refractory strains. Stem Cells 27:383-9 (2009). Read more (PubMed: 19056907) »

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