Overview

  • Product name

    SC-66, Allosteric Akt inhibitor
  • Description

    Allosteric Akt inhibitor
  • Biological description

    Allosteric Akt inhibitor. Interferes with PIP3 binding to Akt's PH domain. Additionally facilitates Akt ubiquitination. Displays anticancer activity in vitro and in vivo.
  • Purity

    > 99%
  • CAS Number

    871361-88-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Jo H  et al. Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. Proc Natl Acad Sci U S A 108:6486-91 (2011). Read more (PubMed: 21464312) »

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