SC79, Akt activator (ab146428)
- Datasheet
- References (2)
Overview
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Product name
SC79, Akt activator -
Description
Akt activator -
Biological description
Akt activator. Binds to the pleckstrin homology domain. Suppress excitotoxicity-induced neuronal death. Shows neuroprotective effects in vivo. Blood-brain barrier permeable. -
CAS Number
305834-79-1 -
Chemical structure
Properties
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Chemical name
2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester -
Molecular weight
364.80 -
Molecular formula
C17H17ClN2O5 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
References
This product has been referenced in:
- So EY & Ouchi T BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction. BMC Cancer 14:548 (2014). Read more (PubMed: 25070371) »
- Su W et al. Doxycycline exerts multiple anti-allergy effects to attenuate murine allergic conjunctivitis and systemic anaphylaxis. Biochem Pharmacol 91:359-68 (2014). Read more (PubMed: 25128381) »
- Jo H et al. Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death. Proc Natl Acad Sci U S A 109:10581-6 (2012). Read more (PubMed: 22689977) »
