Overview

  • Product name

  • Description

    Goat polyclonal to SCAP2/SAPS
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to Human SCAP2/SAPS aa 346-359 (C terminal).
    Sequence:

    (C)GLVPKAYIMEMYDI

  • General notes

     This product was previously labelled as SCAP2

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.05% Tris, 0.5% BSA
  • Concentration information loading...
  • Purity

    Ammonium Sulphate Precipitation
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2484 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 42.2 kDa).
ELISA 1/32000.

Target

  • Function

    May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
  • Tissue specificity

    Ubiquitously expressed. Present in platelets (at protein level).
  • Sequence similarities

    Belongs to the SKAP family.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • Domain

    The SH3 domain interacts with FYB and PTK2B.
  • Post-translational
    modifications

    Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Fyn associated phosphoprotein SKAP55 homologue antibody
    • MGC10411 antibody
    • MGC33 antibody
    • PRAP antibody
    • Pyk2/RAFTK associated protein antibody
    • Pyk2/RAFTK-associated protein antibody
    • RA70 antibody
    • Retinoic acid-induced protein 70 antibody
    • SAPS antibody
    • SKAP-55HOM antibody
    • SKAP-HOM antibody
    • skap2 antibody
    • SKAP2_HUMAN antibody
    • SKAP55 homolog antibody
    • SKAP55R antibody
    • Src associated adaptor protein antibody
    • Src family associated phosphoprotein 2 antibody
    • Src family-associated phosphoprotein 2 antibody
    • src kinase associated phosphoprotein of 55 related protein antibody
    • Src kinase-associated phosphoprotein 2 antibody
    • Src kinase-associated phosphoprotein 55-related protein antibody
    • Src-associated adapter protein with PH and SH3 domains antibody
    see all

Images

  • Anti-SCAP2/SAPS antibody (ab2484) at 0.5 µg/ml + Jurkat lysate at 35 µg

    Predicted band size: 42.2 kDa

References

This product has been referenced in:

  • Haanstra KG  et al. Expression patterns of regulatory T-cell markers in accepted and rejected nonhuman primate kidney allografts. Am J Transplant 7:2236-46 (2007). Read more (PubMed: 17845559) »
See 1 Publication for this product

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There are currently no Customer reviews or Questions for ab2484.
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