Product nameAnti-SCARA5 antibody
See all SCARA5 primary antibodies
DescriptionRabbit polyclonal to SCARA5
Tested applicationsSuitable for: ELISA, ICC, WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
17 amino acid synthetic peptide near the carboxy terminus of Human SCARA5.
- Human Small Intestine tissue; Human liver tissue lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab118894 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.|
|ICC||Use at an assay dependent concentration.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionFerritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
Sequence similaritiesBelongs to the SCARA5 family.
Contains 1 collagen-like domain.
Contains 1 SRCR domain.
Cellular localizationCell membrane.
- Information by UniProt
FormThere are 4 isoforms produced by alternative splicing.
- FLJ23907 antibody
- MGC45780 antibody
- NET33 antibody
This product has been referenced in:
- Dostalova S et al. Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin. Sci Rep 8:8867 (2018). Read more (PubMed: 29891921) »
- Cutrin JC et al. Cancer cell death induced by ferritins and the peculiar role of their labile iron pool. Oncotarget 9:27974-27984 (2018). Read more (PubMed: 29963255) »