Overview

  • Product name

  • Description

    Rabbit polyclonal to SCARA5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Frmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide derived from the N-terminal domain of mouse Scar5.

Properties

Applications

Our Abpromise guarantee covers the use of ab76720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/5000. Predicted molecular weight: 54 kDa.
IHC-Fr 1/100 - 1/1000.

Target

  • Function

    Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
  • Sequence similarities

    Belongs to the SCARA5 family.
    Contains 1 collagen-like domain.
    Contains 1 SRCR domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Form

    There are 4 isoforms produced by alternative splicing.
  • Alternative names

    • FLJ23907 antibody
    • MGC45780 antibody
    • NET33 antibody
    • SCAR5_HUMAN antibody
    • SCARA 5 antibody
    • scara5 antibody
    • Scavenger receptor class A member 5 antibody
    • Scavenger receptor class A, member 5 (putative) antibody
    • Scavenger receptor class A, member 5 antibody
    • Scavenger receptor hlg antibody
    • Tesr antibody
    • Testis expressed scavenger receptor antibody
    see all

References

This product has been referenced in:

  • Kong Q  et al. A Novel Naphthyridine Derivative, 3u, Induces Necroptosis at Low Concentrations and Apoptosis at High Concentrations in Human Melanoma A375 Cells. Int J Mol Sci 19:N/A (2018). Read more (PubMed: 30274263) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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