Key features and details
- Rabbit polyclonal to SCARA5
- Suitable for: IHC-Fr
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-SCARA5 antibody
See all SCARA5 primary antibodies
DescriptionRabbit polyclonal to SCARA5
Tested applicationsSuitable for: IHC-Frmore details
Species reactivityReacts with: Mouse
Predicted to work with: Human
Synthetic peptide derived from the N-terminal domain of mouse Scar5.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab76720 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||1/100 - 1/1000.|
FunctionFerritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
Sequence similaritiesBelongs to the SCARA5 family.
Contains 1 collagen-like domain.
Contains 1 SRCR domain.
Cellular localizationCell membrane.
- Information by UniProt
FormThere are 4 isoforms produced by alternative splicing.
- FLJ23907 antibody
- MGC45780 antibody
- NET33 antibody
ab76720 has been referenced in 1 publication.
- Kong Q et al. A Novel Naphthyridine Derivative, 3u, Induces Necroptosis at Low Concentrations and Apoptosis at High Concentrations in Human Melanoma A375 Cells. Int J Mol Sci 19:N/A (2018). PubMed: 30274263