Overview

  • Product name

  • Description

    Goat polyclonal to SCD1
  • Host species

    Goat
  • Tested applications

    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig
  • Immunogen

    Synthetic peptide:

    RIKRTGDGNYKSG

    , corresponding to C terminal amino acids 347-359 of Human SCD (O00767).

  • Positive control

    • Human Colon and Liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab111301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/64000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
  • Sequence similarities

    Belongs to the fatty acid desaturase family.
  • Domain

    The histidine box domains may contain the active site and/or be involved in metal ion binding.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACOD_HUMAN antibody
    • Acyl-CoA desaturase antibody
    • Delta(9)-desaturase antibody
    • Delta-9 desaturase antibody
    • Delta-9-Desaturase antibody
    • FADS5 antibody
    • Fatty acid desaturase antibody
    • PRO0998 antibody
    • SCD 1 antibody
    • SCD antibody
    • SCD1 antibody
    • Stearoyl-CoA desaturase antibody
    see all

Images

  • Immunohistochemistry Image of Human Colon tissue: Formalin Fixed, Paraffin Embedded (FFPE) and stained with ab111301 at 5µg/ml.
  • Immunohistochemistry Image of Human Liver tissue: Formalin Fixed, Paraffin Embedded (FFPE) and stained with ab111301 at 5µg/ml.

References

This product has been referenced in:

  • Meller S  et al. Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG- and gleason score-specific metabolomic alterations in prostate cancer. Oncotarget 7:1421-38 (2016). IHC-P ; Human . Read more (PubMed: 26623558) »
See 1 Publication for this product

Customer reviews and Q&As

Filter by Application

Filter by Species

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Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Pig Tissue sections (jejunum)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Dako cat#S1699
Permeabilization
No
Specification
jejunum
Blocking step
Dako/Agilent Protein block serum free X090930-2 as blocking agent for 10 minute(s) · Concentration: 1% · Temperature: 25°C
Fixative
Formaldehyde

Dr. Simon Ye

Verified customer

Submitted Oct 04 2019

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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