Anti-SCIN antibody (ab96105)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-SCIN antibody
See all SCIN primary antibodies -
Description
Rabbit polyclonal to SCIN -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat, Cow
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Immunogen
Recombinant protein fragment corresponding to a region within amino acids 281 and 555 of Human SCIN.
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Positive control
- HepG2 whole cell lysate
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab96105 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 80 kDa. |
Target
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Function
Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes. -
Sequence similarities
Belongs to the villin/gelsolin family.
Contains 6 gelsolin-like repeats. -
Cellular localization
Cytoplasm, cytoskeleton. - Information by UniProt
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Database links
- Entrez Gene: 281478 Cow
- Entrez Gene: 85477 Human
- Entrez Gene: 298975 Rat
- Omim: 613416 Human
- SwissProt: Q28046 Cow
- SwissProt: Q9Y6U3 Human
- Unigene: 633359 Human
- Unigene: 655515 Human
see all -
Alternative names
- Adseverin antibody
- ADSV_HUMAN antibody
- KIAA1905 antibody
see all
Images
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Western blot - Anti-SCIN antibody (ab96105)Anti-SCIN antibody (ab96105) at 1/1000 dilution + HepG2 cell lysate at 30 µg
Predicted band size: 80 kDa
Protocols
References
ab96105 has not yet been referenced specifically in any publications.
