Anti-Scn2b antibody (ab138064)
Key features and details
- Rabbit polyclonal to Scn2b
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Scn2b antibody
See all Scn2b primary antibodies -
Description
Rabbit polyclonal to Scn2b -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to internal amino acids of Human Scn2b.
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Positive control
- HepG2 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab138064 was affinity purified from rabbit antiserum by immunogenic peptide affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab138064 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 24 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 24 kDa. |
Target
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Function
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. -
Tissue specificity
Brain specific. -
Sequence similarities
Belongs to the sodium channel auxiliary subunit SCN2B (TC 8.A.17) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 6327 Human
- Entrez Gene: 72821 Mouse
- Entrez Gene: 25349 Rat
- Omim: 601327 Human
- SwissProt: O60939 Human
- SwissProt: Q56A07 Mouse
- SwissProt: P54900 Rat
- Unigene: 129783 Human
see all -
Alternative names
- Neuronal voltage gated sodium channel beta 2 subunit antibody
- Scn 2b antibody
- Scn2b antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab138064 has been referenced in 1 publication.
- Molina-Navarro MM et al. Differential gene expression of cardiac ion channels in human dilated cardiomyopathy. PLoS One 8:e79792 (2013). WB ; Human . PubMed: 24339868