Key features and details
- Mouse monoclonal [7B8] to SCNN1B - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Mouse
- Isotype: IgG1
Product nameAnti-SCNN1B antibody [7B8] - C-terminal
See all SCNN1B primary antibodies
DescriptionMouse monoclonal [7B8] to SCNN1B - C-terminal
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat
- IHC-P: Mouse kidney cortex tissue. WB: Mouse kidney homogenates.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityProtein G purified
Purification notesPurified from TCS.
Our Abpromise guarantee covers the use of ab241050 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 73 kDa.|
FunctionSodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Involvement in diseasePseudohypoaldosteronism 1, autosomal recessive
Bronchiectasis with or without elevated sweat chloride 1
Sequence similaritiesBelongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily.
modificationsPhosphorylated on serine and threonine residues.
Cellular localizationApical cell membrane. Apical membrane of epithelial cells.
- Information by UniProt
- Amiloride sensitive sodium channel subunit beta antibody
- Amiloride-sensitive sodium channel subunit beta antibody
- Beta NaCH antibody
Formalin-fixed, paraffin-embedded mouse kidney cortex tissue stained for SCNN1B with ab241050 at 1/150 dilution in immunohistochemical analysis.
All lanes : Anti-SCNN1B antibody [7B8] - C-terminal (ab241050) at 1/1000 dilution
Lane 1 : Mouse kidney homogenates from a mouse on a low-salt diet
Lane 2 : Mouse kidney homogenates from a mouse on a normal salt diet
Lysates/proteins at 20 µg per lane.
Predicted band size: 73 kDa
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab241050 has not yet been referenced specifically in any publications.