Overview

  • Product name

  • Description

    Goat polyclonal to SCNN1D
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Monkey, Gorilla
  • Immunogen

    Synthetic peptide:

    AGPQPLETLDT

    with a Cysteine residue linker, corresponding to C terminal amino acids 628-638 of Human SCNN1D (NP_002969.2).

  • Positive control

    • Human uterus tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab129274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Preliminary experiments in Human Pancreas and Thymus lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml).
IHC-P Use a concentration of 2.5 - 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
  • Sequence similarities

    Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1D subfamily.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Amiloride sensitive sodium channel subunit delta antibody
    • Amiloride-sensitive sodium channel subunit delta antibody
    • Delta ENaC antibody
    • Delta NaCH antibody
    • Delta-ENaC antibody
    • Delta-NaCH antibody
    • DNACH antibody
    • ENaC Delta antibody
    • ENaCD antibody
    • ENaCdelta antibody
    • Epithelial Na(+) channel subunit delta antibody
    • MGC149710 antibody
    • MGC149711 antibody
    • Nonvoltage gated sodium channel 1 subunit delta antibody
    • Nonvoltage-gated sodium channel 1 subunit delta antibody
    • SCNED antibody
    • SCNN1D antibody
    • SCNND_HUMAN antibody
    • Sodium channel, nonvoltage gated 1, delta antibody
    see all

Images

  • ab129274, at 3.75 µg/ml, staining SCNN1D in Formalin-fixed, Paraffin-embedded Human Uterus tissue by Immunohistochemistry.

References

ab129274 has not yet been referenced specifically in any publications.

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