Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: Tris citrate/phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab15090 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||1/100 - 1/750.|
FunctionMajor component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
DomainConsists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.
Cellular localizationNucleus. Chromosome. In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.
- Information by UniProt
- Cancer/testis antigen 8 antibody
- CT8 antibody
- HOM TES 14 antibody
This product has been referenced in:
- Shi B et al. MORC2B is essential for meiotic progression and fertility. PLoS Genet 14:e1007175 (2018). Read more (PubMed: 29329290) »
- Biswas U et al. SMC1a Substitutes for Many Meiotic Functions of SMC1ß but Cannot Protect Telomeres from Damage. Curr Biol 28:249-261.e4 (2018). Read more (PubMed: 29337080) »