Product nameAnti-SCP3 antibody [EPR12695(B)]
See all SCP3 primary antibodies
DescriptionRabbit monoclonal [EPR12695(B)] to SCP3
Tested applicationsSuitable for: Flow Cyt, WBmore details
Unsuitable for: ICC/IF,IHC-P or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SCP3 aa 150 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
Database link: Q8IZU3
- Human testis, Human seminoma, Jurkat and HepG2 lysates; Jurkat cells.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab181354 in the following tested applications.
|Flow Cyt||1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
|WB||1/1000 - 1/10000. Predicted molecular weight: 28 kDa.|
FunctionComponent of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development.
Involvement in diseaseDefects in SYCP3 are a cause of azoospermia due to perturbations of meiosis (AZSPM) [MIM:270960]. AZSPM is a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes.
Sequence similaritiesBelongs to the XLR/SYCP3 family.
Cellular localizationNucleus. In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.
- Information by UniProt
- choline phosphotransferase 1 antibody
- chpt1 antibody
- COR 1 antibody
Flow cytometric analysis of permeabilized Jurkat cells labeling SCP3 with ab181354 at 1/10 dilution (red) compared to a rabbit IgG negative control (green).
All lanes : Anti-SCP3 antibody [EPR12695(B)] (ab181354) at 1/1000 dilution
Lane 1 : Human testis lysate
Lane 2 : Human seminoma lysate
Lane 3 : Jurkat cell lysate
Lane 4 : HepG2 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 28 kDa
ab181354 has not yet been referenced specifically in any publications.