Key features and details
- Rabbit polyclonal to Scramblase 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Scramblase 1 antibody
See all Scramblase 1 primary antibodies
DescriptionRabbit polyclonal to Scramblase 1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment, corresponding to amino acids 134-300 of Human Scramblase 1 (BC021100).
- HeLa cell lysate for western-blot, formalin-fixed paraffin-embedded human fetal kidney for IHC-P
FormLyophilized:Reconstitute in 200µl of sterile water
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab128696 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/2000. Predicted molecular weight: 35 kDa.|
|IHC-P||1/100 - 1/500.|
FunctionMay mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.
Tissue specificityExpressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.
Sequence similaritiesBelongs to the phospholipid scramblase family.
modificationsKnown to be palmitoylated at one, yet undefined, site.
- Information by UniProt
- Ca(2+) dependent phospholipid scramblase 1 antibody
- Ca(2+)-dependent phospholipid scramblase 1 antibody
- Erythrocyte phospholipid scramblase antibody
ab128696 has not yet been referenced specifically in any publications.