Key features and details
- Rabbit polyclonal to SCUBE1
- Suitable for: ICC/IF, WB, ICC
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SCUBE1 antibody
See all SCUBE1 primary antibodies
DescriptionRabbit polyclonal to SCUBE1
Specificityab105358 is predicted to not crossreact with other SCUBE members.
Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
Species reactivityReacts with: Human
A 14 amino acid peptide near the center of Human SCUBE1 (NP_766638).
- WB: Daudi cell lysate ICC: Daudi cells
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab105358 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 108 kDa.|
|ICC||Use a concentration of 20 µg/ml.|
FunctionCould function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Tissue specificityDetected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.
Sequence similaritiesContains 1 CUB domain.
Contains 9 EGF-like domains.
Could be proteolytically cleaved to release a smaller active fragment.
Cellular localizationSecreted. Cell membrane.
- Information by UniProt
- SCUB1_HUMAN antibody
- SCUBE 1 antibody
- SCUBE1 antibody
ab105358 has been referenced in 1 publication.
- Del Valle I et al. A genomic atlas of human adrenal and gonad development. Wellcome Open Res 2:25 (2017). IHC ; Human . PubMed: 28459107