Anti-SCYL1 antibody (ab229745)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-SCYL1 antibody
See all SCYL1 primary antibodies -
Description
Rabbit polyclonal to SCYL1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human SCYL1 aa 460-740.
Database link: Q96KG9 -
Positive control
- IHC-P: Human pancreatic tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab229745 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/20 - 1/200. |
Target
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Function
Regulates COPI-mediated retrograde traffic. Has no detectable kinase activity in vitro.
Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the protein kinase superfamily.
Contains 3 HEAT repeats.
Contains 1 protein kinase domain. -
Domain
The protein kinase domain is predicted to be catalytically inactive. -
Cellular localization
Nucleus; Cytoplasm > cytoskeleton > centrosome. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus > cis-Golgi network. Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner; Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasmic during interphase and centrosomal during mitosis, it localizes to the centrosomes in a microtubule-independent manner and Cytoplasm. Cytoplasmic throughout the cell cycle. - Information by UniProt
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Database links
- Entrez Gene: 57410 Human
- Omim: 607982 Human
- SwissProt: Q96KG9 Human
- Unigene: 238839 Human
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Alternative names
- Coated vesicle associated kinase of 90 kDa antibody
- Coated vesicle-associated kinase of 90 kDa antibody
- CVAK90 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SCYL1 antibody (ab229745)Paraffin-embedded human pancreatic tissue stained for SCYL1 using ab229745 at 1/100 dilution in immunohistochemical analysis.
Datasheets and documents
References
ab229745 has not yet been referenced specifically in any publications.
