Overview

  • Product name

  • Description

    Rabbit polyclonal to SCYL1BP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IPmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human SCYL1BP1 aa 325-375. The exact sequence is proprietary.
    Database link: Q5T7V8

  • Positive control

    • IP: HeLa whole cell lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: Tris buffered saline, 0.1% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab241214 was affinity purified using an epitope specific to SCYL1BP1 immobilized on solid support.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab241214 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.

Use 8 - 15 µl/mg lysate.

Target

  • Involvement in disease

    Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
  • Sequence similarities

    Belongs to the GORAB family.
  • Cellular localization

    Cytoplasm. Golgi apparatus.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ11752 antibody
    • GO antibody
    • Golgin RAB6 interacting antibody
    • GORAB antibody
    • GORAB_HUMAN antibody
    • hNTKL BP1 antibody
    • hNTKL-BP1 antibody
    • MGC51263 antibody
    • MGC70512 antibody
    • N terminal kinase like binding protein 1 antibody
    • N-terminal kinase-like-binding protein 1 antibody
    • NTKL binding protein 1 antibody
    • NTKL BP1 antibody
    • NTKL-binding protein 1 antibody
    • NTKL-BP1 antibody
    • NTKLBP 1 antibody
    • NTKLBP1 antibody
    • OTTHUMP00000033164 antibody
    • RAB6-interacting golgin antibody
    • RP11 545I10.1 antibody
    • SCY1 like 1 binding protein 1 antibody
    • SCY1-like 1-binding protein 1 antibody
    • SCYL1 binding protein 1 antibody
    • SCYL1 BP1 antibody
    • SCYL1-binding protein 1 antibody
    • SCYL1-BP1 antibody
    • SCYL1BP1 antibody
    see all

Images

  • SCYL1BP1 was immunoprecipitated from HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab241214 at 8 µl/reaction. Western blot was performed from the immunoprecipitate using ab241214 at 1/1000 dilution.

    Lane 1: ab241214 IP in HeLa whole cell lysate.
    Lane 2: Control IgG IP in HeLa whole cell lysate.

    Detection: Chemiluminescence with exposure time of 3 minutes.

    Lysates prepared in NETN lysis buffer.

References

ab241214 has not yet been referenced specifically in any publications.

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