Overview

  • Product name

    SD 169, ATP-competitive p38alpha MAPK inhibitor
  • Description

    Potent, selective and ATP-competitive p38α MAPK inhibitor
  • Biological description

    Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.
  • Purity

    > 99%
  • CAS Number

    1670-87-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Medicherla S  et al. Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes. J Pharmacol Exp Ther 318:99-107 (2006). Read more (PubMed: 16603672) »
  • Myers RR  et al. Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol 184:606-14 (2003). Read more (PubMed: 14769353) »

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