Overview

  • Product name

  • Description

    Goat polyclonal to SDCCAG8
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human SDCCAG8 aa 469-483 (internal sequence) (Cysteine residue). (NP_006633.1).
    Sequence:

    DEAEKEHREFRAKTN


    Database link: Q86SQ7

  • Positive control

    • Human brain cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab211283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.
  • Tissue specificity

    Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
  • Involvement in disease

    Senior-Loken syndrome 7 (SLSN7) [MIM:613615]: A renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Cellular localization

    Cytoplasm and Cytoplasm > cytoskeleton > centrosome > centriole. Cell junction. Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.
  • Information by UniProt
  • Database links

  • Alternative names

    • Antigen NY CO 8 antibody
    • Antigen NY-CO-8 antibody
    • BBS16 antibody
    • CCCAP antibody
    • CCCAP SLSN7 antibody
    • Centrosomal colon cancer autoantigen protein antibody
    • hCCCAP antibody
    • HSPC085 antibody
    • NPHP10 antibody
    • NPHP10 gene antibody
    • NY-CO-8 antibody
    • Sdccag8 antibody
    • SDCG8_HUMAN antibody
    • Serologically defined colon cancer antigen 8 antibody
    • Serologically defined colon cancer antigen 8 homolog antibody
    • SLSN7 antibody
    • SLSN7 gene antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain cortex tissue labeling SDCCAG8 with ab211283 at 5 µg/ml.

References

ab211283 has not yet been referenced specifically in any publications.

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