Anti-SDHB antibody [21A11AE7] (ab14714)

Mouse monoclonal SDHB antibody [21A11AE7]. Validated in WB, IHC, ICC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Hamster, Cow, Human, Pig, Zebrafish. Cited in 128 publication(s).

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ab14714 has been referenced in 131 publications.

  • Gentric G  et al. PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers. Cell Metab 29:156-173.e10 (2019). PubMed: 30244973
  • Wang H  et al. ?-Tocotrienol inhibits oxidative phosphorylation and triggers apoptosis by inhibiting mitochondrial complex I subunit NDUFB8 and complex II subunit SDHB. Toxicology 417:42-53 (2019). PubMed: 30769052
  • Ma B  et al. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nat Commun 10:1034 (2019). PubMed: 30833558
  • Xiao Z  et al. SDHB downregulation facilitates the proliferation and invasion of colorectal cancer through AMPK functions excluding those involved in the modulation of aerobic glycolysis. Exp Ther Med 15:864-872 (2018). PubMed: 29399091
  • Kuang Y  et al. Oxaloacetate induces apoptosis in HepG2 cells via inhibition of glycolysis. Cancer Med 7:1416-1429 (2018). PubMed: 29533007
  • Zagnoli-Vieira G  et al. Confirming TDP2 mutation in spinocerebellar ataxia autosomal recessive 23 (SCAR23). Neurol Genet 4:e262 (2018). PubMed: 30109272
  • Turner N  et al. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nat Commun 9:3165 (2018). PubMed: 30131496
  • Richter S  et al. Primary fibroblast co-culture stimulates growth and metabolism in Sdhb-impaired mouse pheochromocytoma MTT cells. Cell Tissue Res 374:473-485 (2018). PubMed: 30159755
  • Ngo DT  et al. Oxidative Modifications of Mitochondrial Complex II are associated with insulin resistance of visceral fat in obesity. Am J Physiol Endocrinol Metab N/A:N/A (2018). PubMed: 30576243
  • Pareek G  et al. Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. Cell Death Dis 9:304 (2018). PubMed: 29467464
  • Krysciak K  et al. Adaptation of motor unit contractile properties in rat medial gastrocnemius to treadmill endurance training: Relationship to muscle mitochondrial biogenesis. PLoS One 13:e0195704 (2018). PubMed: 29672614
  • Bezawork-Geleta A  et al. Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints. Nat Commun 9:2221 (2018). PubMed: 29880867
  • Kelly AC  et al. Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells. Mol Cell Endocrinol 473:136-145 (2018). WB . PubMed: 29360563
  • Askeland G  et al. Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients. Sci Rep 8:9817 (2018). PubMed: 29959348
  • Sulkowski PL  et al. Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair. Nat Genet 50:1086-1092 (2018). PubMed: 30013182
  • Binek A  et al. Proteomic footprint of myocardial ischemia/reperfusion injury: Longitudinal study of the at-risk and remote regions in the pig model. Sci Rep 7:12343 (2017). WB ; Pig . PubMed: 28955040
  • Kaemmerer D  et al. Evaluation of somatostatin, CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas. Oncotarget 8:89958-89969 (2017). IHC-P ; Human . PubMed: 29163802
  • Liu Y  et al. Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells. Nat Commun 8:1212 (2017). PubMed: 29089484
  • Perks KL  et al. Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677 (2017). PubMed: 28835921
  • Cohen J  et al. Astrocyte Senescence and Metabolic Changes in Response to HIV Antiretroviral Therapy Drugs. Front Aging Neurosci 9:281 (2017). PubMed: 28900395
  • Liu W  et al. Clinicopathologic study of succinate-dehydrogenase-deficient gastrointestinal stromal tumors: A single-institutional experience in China. Medicine (Baltimore) 96:e7668 (2017). IHC-P ; Human . PubMed: 28796048
  • Rohlenova K  et al. Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2(high) Breast Cancer. Antioxid Redox Signal 26:84-103 (2017). WB ; Human . PubMed: 27392540
  • Stram AR  et al. Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich's ataxia cardiomyopathy. PLoS One 12:e0178354 (2017). WB ; Mouse . PubMed: 28542596
  • Tegelberg S  et al. Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73 (2017). PubMed: 28427446
  • Kitazawa S  et al. Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. Oncotarget 8:28922-28938 (2017). WB . PubMed: 28423651
  • Feichtinger RG  et al. Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies. Am J Hum Genet 101:525-538 (2017). PubMed: 28942965
  • Hauck L  et al. Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death. PLoS One 12:e0189861 (2017). PubMed: 29267372
  • Lopez-Cruzan M  et al. Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment. Cell Death Discov 2:N/A (2016). PubMed: 27019748
  • Burridge PW  et al. Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Nat Med 22:547-56 (2016). PubMed: 27089514
  • Schubert C  et al. Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor ß. Biol Sex Differ 7:53 (2016). PubMed: 27688871
  • Sverdlov AL  et al. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc 5:N/A (2016). WB ; Mouse . PubMed: 26755553
  • Pérez-Pérez R  et al. COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation. Cell Rep 16:2387-98 (2016). WB . PubMed: 27545886
  • Bezawork-Geleta A  et al. The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells. J Biol Chem 291:21414-21420 (2016). PubMed: 27587393
  • Zurita Rendón O  et al. A Mutation in the Flavin Adenine Dinucleotide-Dependent Oxidoreductase FOXRED1 Results in Cell-Type-Specific Assembly Defects in Oxidative Phosphorylation Complexes I and II. Mol Cell Biol 36:2132-40 (2016). PubMed: 27215383
  • Naseri NN  et al. Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients. PLoS One 11:e0160384 (2016). WB . PubMed: 27611087
  • Her YF  et al. Oxygen concentration controls epigenetic effects in models of familial paraganglioma. PLoS One 10:e0127471 (2015). IHC-P ; Human . PubMed: 25985299
  • Gouspillou G  et al. Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep 5:8717 (2015). WB ; Mouse . PubMed: 25732599
  • Naseri NN  et al. Abnormalities in the tricarboxylic Acid cycle in Huntington disease and in a Huntington disease mouse model. J Neuropathol Exp Neurol 74:527-37 (2015). PubMed: 25978848
  • Vincent G  et al. Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51 (2015). WB . PubMed: 25759671
  • Nordsborg NB  et al. Oxidative capacity and glycogen content increase more in arm than leg muscle in sedentary women after intense training. J Appl Physiol (1985) 119:116-23 (2015). PubMed: 26023221
  • Ferreira-da-Silva A  et al. Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration. PLoS One 10:e0122308 (2015). PubMed: 25822260
  • Nordby P  et al. Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial. J Appl Physiol (1985) 118:803-10 (2015). PubMed: 25614598
  • Vega-Naredo I  et al. Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells. Cell Death Differ : (2014). PubMed: 24832466
  • Sverdlov AL  et al. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol N/A:N/A (2014). WB ; Mouse . PubMed: 25109264
  • Gouspillou G  et al. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J 28:1621-33 (2014). WB ; Human . PubMed: 24371120
  • Davoudi M  et al. Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive complex III deficiency. PLoS One 9:e86767 (2014). WB ; Mouse . PubMed: 24466228
  • Ghosh A  et al. Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency. Hum Mol Genet N/A:N/A (2014). WB . PubMed: 24549041
  • Gill AJ  et al. Succinate dehydrogenase deficiency is rare in pituitary adenomas. Am J Surg Pathol 38:560-6 (2014). IHC-P ; Human . PubMed: 24625421
  • Lee PW  et al. Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess. Int J Surg Pathol 22:286-90 (2014). PubMed: 23794494
  • Huang R  et al. Megakaryocytic Differentiation of K562 Cells Induced by PMA Reduced the Activity of Respiratory Chain Complex IV. PLoS One 9:e96246 (2014). PubMed: 24817082
  • Kovács-Bogdán E  et al. Reconstitution of the mitochondrial calcium uniporter in yeast. Proc Natl Acad Sci U S A 111:8985-90 (2014). WB ; Human . PubMed: 24889638
  • Hiniker A  et al. Axial mitochondrial myopathy in a patient with rapidly progressive adult-onset scoliosis. Acta Neuropathol Commun 2:137 (2014). IHC-Fr ; Human . PubMed: 25223649
  • Gill AJ  et al. Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients. Am J Surg Pathol 38:1588-602 (2014). IHC ; Human . PubMed: 25025441
  • Kim HM  et al. Site-specific metabolic phenotypes in metastatic breast cancer. J Transl Med 12:354 (2014). PubMed: 25496516
  • Andersen TR  et al. A preliminary study: effects of football training on glucose control, body composition, and performance in men with type 2 diabetes. Scand J Med Sci Sports 24 Suppl 1:43-56 (2014). PubMed: 24903461
  • Plovanich M  et al. MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling. PLoS One 8:e55785 (2013). WB ; Human . PubMed: 23409044
  • Kelly L  et al. Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]. PLoS One 8:e64102 (2013). IHC-P ; Human . PubMed: 23717541
  • Belinsky MG  et al. Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors. Front Oncol 3:117 (2013). IHC-P ; Human . PubMed: 23730622
  • Dwight T  et al. Familial SDHA mutation associated with pituitary adenoma and pheochromocytoma/paraganglioma. J Clin Endocrinol Metab 98:E1103-8 (2013). PubMed: 23633203
  • Killian JK  et al. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Discov 3:648-57 (2013). PubMed: 23550148
  • Chae YC  et al. Landscape of the mitochondrial Hsp90 metabolome in tumours. Nat Commun 4:2139 (2013). PubMed: 23842546
  • Kovárová N  et al. High molecular weight forms of mammalian respiratory chain complex II. PLoS One 8:e71869 (2013). WB ; Human . PubMed: 23967256
  • Habersetzer J  et al. Human F1F0 ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter? PLoS One 8:e75429 (2013). WB ; Human . PubMed: 24098383
  • Jacobs RA  et al. Fast-Twitch Glycolytic Skeletal Muscle Is Predisposed to Age-Induced Impairments in Mitochondrial Function. J Gerontol A Biol Sci Med Sci : (2013). PubMed: 23371970
  • Cama A  et al. Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling. Acta Neuropathol 126:575-94 (2013). IHC . PubMed: 23955600
  • Jourdain AA  et al. GRSF1 regulates RNA processing in mitochondrial RNA granules. Cell Metab 17:399-410 (2013). PubMed: 23473034
  • Jacobs RA  et al. The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. Exp Physiol 98:908-21 (2013). PubMed: 23180810
  • Welander J  et al. Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas. Hum Mol Genet 21:5406-16 (2012). PubMed: 23010473
  • Chou A  et al. Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression. Mod Pathol 25:1307-13 (2012). PubMed: 22555179
  • van Wietmarschen N  et al. The Mammalian Proteins MMS19, MIP18, and ANT2 Are Involved in Cytoplasmic Iron-Sulfur Cluster Protein Assembly. J Biol Chem 287:43351-8 (2012). PubMed: 23150669
  • Cameselle-Teijeiro J  et al. Absence of the BRAF and the GRIM-19 mutations in oncocytic (Hürthle cell) solid cell nests of the thyroid. Am J Clin Pathol 137:612-8 (2012). IHC-P ; Human . PubMed: 22431538
  • He J  et al. Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis. Nucleic Acids Res : (2012). WB ; Human . PubMed: 22453275
  • Ferreira M  et al. Progressive cavitating leukoencephalopathy associated with respiratory chain complex I deficiency and a novel mutation in NDUFS1. Neurogenetics 12:9-17 (2011). PubMed: 21203893
  • Strub GM  et al. Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration. FASEB J 25:600-12 (2011). PubMed: 20959514
  • Gerards M  et al. Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene. Brain 134:210-9 (2011). PubMed: 20929961
  • Cameron JM  et al. Complex V TMEM70 deficiency results in mitochondrial nucleoid disorganization. Mitochondrion 11:191-9 (2011). PubMed: 20920610
  • Celestino R  et al. A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney-Stratakis dyad. Fam Cancer : (2011). PubMed: 22160509
  • Shan Y & Cortopassi G HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis. Hum Mol Genet : (2011). PubMed: 22171070
  • Wang JH  et al. Succinate Dehydrogenase Subunit B (SDHB) Is Expressed in Neurofibromatosis 1-Associated Gastrointestinal Stromal Tumors (Gists): Implications for the SDHB Expression Based Classification of Gists. J Cancer 2:90-3 (2011). IHC ; Human . PubMed: 21479127
  • Gill AJ  et al. Renal tumors associated with germline SDHB mutation show distinctive morphology. Am J Surg Pathol 35:1578-85 (2011). IHC ; Human . PubMed: 21934479
  • Miettinen M  et al. Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age. Am J Surg Pathol 35:1712-21 (2011). Human . PubMed: 21997692
  • Rossi S  et al. Natural history of imatinib-naive GISTs: a retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables. Am J Surg Pathol 35:1646-56 (2011). PubMed: 21997685
  • Gegg ME  et al. Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet 19:4861-70 (2010). PubMed: 20871098
  • Fassone E  et al. FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy. Hum Mol Genet 19:4837-47 (2010). PubMed: 20858599
  • Tuppen HA  et al. The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families. Brain 133:2952-63 (2010). PubMed: 20819849
  • Mayr JA  et al. Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit. Hum Mol Genet 19:3430-9 (2010). PubMed: 20566710
  • Calore F  et al. Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA. Cell Death Differ 17:1707-16 (2010). PubMed: 20431599
  • Ylikallio E  et al. High mitochondrial DNA copy number has detrimental effects in mice. Hum Mol Genet 19:2695-705 (2010). PubMed: 20413656
  • Walmsley SJ  et al. Proteomic analysis of brush-border membrane vesicles isolated from purified proximal convoluted tubules. Am J Physiol Renal Physiol 298:F1323-31 (2010). PubMed: 20219825
  • Ahola-Erkkilä S  et al. Ketogenic diet slows down mitochondrial myopathy progression in mice. Hum Mol Genet 19:1974-84 (2010). PubMed: 20167576
  • Wydro M  et al. Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition. Nucleic Acids Res 38:3732-42 (2010). PubMed: 20144953
  • Cimen H  et al. Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 49:304-11 (2010). PubMed: 20000467
  • Mracek T  et al. Downregulation of zinc-{alpha}2-glycoprotein in adipose tissue and liver of obese ob/ob mice and by tumour necrosis factor-alpha in adipocytes. J Endocrinol 204:165-72 (2010). PubMed: 19934249
  • Feichtinger RG  et al. Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma. BMC Cancer 10:149 (2010). PubMed: 20398431
  • Fogal V  et al. Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol 30:1303-18 (2010). PubMed: 20100866
  • Kachadourian R  et al. Casiopeína IIgly-induced oxidative stress and mitochondrial dysfunction in human lung cancer A549 and H157 cells. Toxicology 268:176-83 (2010). PubMed: 20026372
  • Gerards M  et al. Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome. J Med Genet 47:507-12 (2010). PubMed: 19542079
  • Gill AJ  et al. Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC, and SDHD in paraganglioma-pheochromocytoma syndromes. Hum Pathol 41:805-14 (2010). IHC-P ; Human . PubMed: 20236688
  • Brennan LA  et al. Deletion of mouse MsrA results in HBO-induced cataract: MsrA repairs mitochondrial cytochrome c. Mol Vis 15:985-99 (2009). PubMed: 19461988
  • De Maria A  et al. Calpain expression and activity during lens fiber cell differentiation. J Biol Chem 284:13542-50 (2009). PubMed: 19269960
  • Yahata N  et al. Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration. J Neurosci 29:6276-84 (2009). PubMed: 19439605
  • Jeong K  et al. Modulation of the caveolin-3 localization to caveolae and STAT3 to mitochondria by catecholamine-induced cardiac hypertrophy in H9c2 cardiomyoblasts. Exp Mol Med 41:226-35 (2009). PubMed: 19299911
  • Hanein S  et al. TMEM126A, encoding a mitochondrial protein, is mutated in autosomal-recessive nonsyndromic optic atrophy. Am J Hum Genet 84:493-8 (2009). PubMed: 19327736
  • Son M  et al. Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo. Neurobiol Dis 34:155-62 (2009). PubMed: 19320055
  • Murayama K  et al. Intractable secretory diarrhea in a Japanese boy with mitochondrial respiratory chain complex I deficiency. Eur J Pediatr 168:297-302 (2009). PubMed: 18560889
  • Horvath R  et al. Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy. Brain 132:3165-74 (2009). PubMed: 19720722
  • Gómez LA  et al. Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart. Arch Biochem Biophys 490:30-5 (2009). PubMed: 19679098
  • Caro P  et al. Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver. Biogerontology 10:579-92 (2009). PubMed: 19039676
  • Burnichon N  et al. The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. J Clin Endocrinol Metab 94:2817-27 (2009). PubMed: 19454582
  • Hakonen AH  et al. Infantile-onset spinocerebellar ataxia and mitochondrial recessive ataxia syndrome are associated with neuronal complex I defect and mtDNA depletion. Hum Mol Genet 17:3822-35 (2008). PubMed: 18775955
  • Calvaruso MA  et al. Electrophoresis techniques to investigate defects in oxidative phosphorylation. Methods 46:281-7 (2008). PubMed: 18948205
  • Rorbach J  et al. The human mitochondrial ribosome recycling factor is essential for cell viability. Nucleic Acids Res 36:5787-99 (2008). PubMed: 18782833
  • Ahn BH  et al. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci U S A 105:14447-52 (2008). PubMed: 18794531
  • Lyly A  et al. Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism. Hum Mol Genet 17:1406-17 (2008). PubMed: 18245779
  • Son M  et al. Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein. J Biol Chem 283:12267-75 (2008). PubMed: 18334481
  • Fornuskova D  et al. The impact of mitochondrial tRNA mutations on the amount of ATP synthase differs in the brain compared to other tissues. Biochim Biophys Acta 1782:317-25 (2008). PubMed: 18319067
  • Lebon S  et al. A novel mutation of the NDUFS7 gene leads to activation of a cryptic exon and impaired assembly of mitochondrial complex I in a patient with Leigh syndrome. Mol Genet Metab 92:104-8 (2007). PubMed: 17604671
  • Canal F  et al. Regulation of the cysteine desulfurase Nfs1 and the scaffold protein IscU in macrophages stimulated with interferon-gamma and lipopolysaccharide. Arch Biochem Biophys 465:282-92 (2007). PubMed: 17603005
  • Ramanujan VK & Herman BA Aging process modulates nonlinear dynamics in liver cell metabolism. J Biol Chem 282:19217-26 (2007). PubMed: 17446172
  • Li Y  et al. An assembled complex IV maintains the stability and activity of complex I in mammalian mitochondria. J Biol Chem 282:17557-62 (2007). PubMed: 17452320
  • Park JS  et al. Yeast NDI1 improves oxidative phosphorylation capacity and increases protection against oxidative stress and cell death in cells carrying a Leber's hereditary optic neuropathy mutation. Biochim Biophys Acta 1772:533-42 (2007). PubMed: 17320357
  • Folbergrová J  et al. Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizures. Exp Neurol 204:597-609 (2007). PubMed: 17270175
  • Carrozzo R  et al. SUCLA2 mutations are associated with mild methylmalonic aciduria, Leigh-like encephalomyopathy, dystonia and deafness. Brain 130:862-74 (2007). PubMed: 17301081
  • Yoon YS  et al. Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1. J Cell Physiol 209:468-80 (2006). PubMed: 16883569
  • Powelka AM  et al. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest 116:125-36 (2006). WB ; Mouse . PubMed: 16374519
  • Lelliott CJ  et al. Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol 4:e369 (2006). PubMed: 17090215
  • Hori O  et al. Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease. J Cell Biol 157:1151-60 (2002). PubMed: 12082077
  • Hanson BJ  et al. An immunocytochemical approach to detection of mitochondrial disorders. J Histochem Cytochem 50:1281-8 (2002). PubMed: 12364561
  • Hanson BJ  et al. Cytochrome c oxidase-deficient patients have distinct subunit assembly profiles. J Biol Chem 276:16296-301 (2001). PubMed: 11278850
  • Dey R  et al. Functional constraints of nuclear-mitochondrial DNA interactions in xenomitochondrial rodent cell lines. J Biol Chem 275:31520-7 (2000). PubMed: 10908562
  • Marusich MF  et al. Expression of mtDNA and nDNA encoded respiratory chain proteins in chemically and genetically-derived Rho0 human fibroblasts: a comparison of subunit proteins in normal fibroblasts treated with ethidium bromide and fibroblasts from a patient with mtDNA depletion syndrome. Biochim Biophys Acta 1362:145-59 (1997). PubMed: 9540845

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