Anti-SDPR antibody (ab76867)
Key features and details
- Mouse polyclonal to SDPR
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-SDPR antibody -
Description
Mouse polyclonal to SDPR -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human SDPR aa 1-450. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
-
Positive control
- transfected 293T cell line
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab76867 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (2) |
1/500 - 1/1000. Predicted molecular weight: 47 kDa.
|
Notes |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 47 kDa. |
Target
-
Function
May play a role in targeting PRKCA to caveolae. -
Tissue specificity
Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. -
Sequence similarities
Belongs to the PTRF/SDPR family. -
Post-translational
modificationsPhosphorylated on Ser residues. -
Cellular localization
Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae. - Information by UniProt
-
Database links
- Entrez Gene: 8436 Human
- Omim: 606728 Human
- SwissProt: O95810 Human
- Unigene: 26530 Human
-
Alternative names
- Cavin 2 antibody
- Cavin-2 antibody
- Phosphatidylserine binding protein antibody
see all
Images
-
All lanes : Anti-SDPR antibody (ab76867) at 1/500 dilution
Lane 1 : SDPR transfected 293T cell line
Lane 2 : non transfected 293T cell line
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 47 kDa
Observed band size: 72 kDa why is the actual band size different from the predicted?
Datasheets and documents
-
Datasheet download
References (2)
ab76867 has been referenced in 2 publications.
- Matthaeus C et al. The molecular organization of differentially curved caveolae indicates bendable structural units at the plasma membrane. Nat Commun 13:7234 (2022). PubMed: 36433988
- Tian Y et al. Integrated Bioinformatic Analysis of the Expression and Prognosis of Caveolae-Related Genes in Human Breast Cancer. Front Oncol 11:703501 (2021). PubMed: 34513683