• Product name
  • Description
    Rabbit polyclonal to SEC13L1
  • Host species
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Horse, Dog, Chimpanzee, Ferret, Cynomolgus monkey, Rhesus monkey, Gorilla, Orangutan, Bat
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 270-320 of Human SEC13L1 (NP_899195.1).

  • Positive control
    • 293T, HeLa, Jurkat, mouse TCMK1 and mouse NIH 3T3 whole cell lysates.



Our Abpromise guarantee covers the use of ab168824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 35 kDa.
IP Use at 2-10 µg/mg of lysate.


  • Function
    Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles.
  • Sequence similarities
    Belongs to the WD repeat SEC13 family.
    Contains 6 WD repeats.
  • Cellular localization
    Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. In interphase, localizes at both sides of the NPC.
  • Information by UniProt
  • Database links
  • Form
    It is a constituent of the endoplasmic reticulum and the nuclear pore complex. Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Cellular location: Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Nuclear pore complex, Nucleus.
  • Alternative names
    • D3S1231E antibody
    • Npp 20 antibody
    • Npp20 antibody
    • Protein SEC13 homolog antibody
    • SEC13 (S. cerevisiae) like 1 antibody
    • Sec13 antibody
    • SEC13 homolog (S. cerevisiae) antibody
    • SEC13 homolog antibody
    • SEC13 like 1 (S. cerevisiae) antibody
    • SEC13 like 1 isoform antibody
    • SEC13 like protein 1 antibody
    • SEC13 protein antibody
    • SEC13 related protein antibody
    • SEC13-like protein 1 antibody
    • SEC13-related protein antibody
    • SEC13_HUMAN antibody
    • SEC13R antibody
    see all


  • All lanes : Anti-SEC13L1 antibody (ab168824) at 0.1 µg/ml

    Lane 1 : 293T whole cell lysate
    Lane 2 : HeLa whole cell lysate
    Lane 3 : Jurkat whole cell lysate
    Lane 4 : TCMK1 whole cell lysate
    Lane 5 : NIH 3T3 whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 35 kDa

    Exposure time: 10 seconds
  • Detection of SEC13L1 in Immunoprecipitates of 293T whole cell lysate (1 mg for IP, 20% of IP loaded) using ab168824 at 6 µg/mg lysate for IP (Lane 1) and at 1 µg/ml for subsequent Western blot detection. Lane 2 represents control IgG IP.
    Detection: Chemiluminescence with an exposure time of 10 seconds.


This product has been referenced in:
  • Fan J  et al. cTAGE5 deletion in pancreatic ß cells impairs proinsulin trafficking and insulin biogenesis in mice. J Cell Biol 216:4153-4164 (2017). Read more (PubMed: 29133483) »
See 1 Publication for this product

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