Overview

  • Product name

  • Description

    Rabbit polyclonal to SEC13L1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Zebrafish
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 1 and 289 of Human SEC13L1 (NP_899195).

  • Positive control

    • 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96044 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 36 kDa.

Target

  • Function

    Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles.
  • Sequence similarities

    Belongs to the WD repeat SEC13 family.
    Contains 6 WD repeats.
  • Cellular localization

    Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. In interphase, localizes at both sides of the NPC.
  • Information by UniProt
  • Database links

  • Form

    It is a constituent of the endoplasmic reticulum and the nuclear pore complex. Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Cellular location: Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Nuclear pore complex, Nucleus.
  • Alternative names

    • D3S1231E antibody
    • Npp 20 antibody
    • Npp20 antibody
    • Protein SEC13 homolog antibody
    • SEC13 (S. cerevisiae) like 1 antibody
    • Sec13 antibody
    • SEC13 homolog (S. cerevisiae) antibody
    • SEC13 homolog antibody
    • SEC13 like 1 (S. cerevisiae) antibody
    • SEC13 like 1 isoform antibody
    • SEC13 like protein 1 antibody
    • SEC13 protein antibody
    • SEC13 related protein antibody
    • SEC13-like protein 1 antibody
    • SEC13-related protein antibody
    • SEC13_HUMAN antibody
    • SEC13R antibody
    see all

Images

  • All lanes : Anti-SEC13L1 antibody (ab96044) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : H1299 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 36 kDa



    10% SDS PAGE

References

This product has been referenced in:

  • Fryer LG  et al. The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis. J Biol Chem 289:4244-61 (2014). WB ; Human . Read more (PubMed: 24338480) »
See 1 Publication for this product

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