Overview

  • Product name
  • Description
    Rabbit polyclonal to SEC14L2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Pig
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 37-250 of Human SEC14L2 (UniProt O76054).

  • Positive control
    • U87-MG whole cell lysate; H1299 xenograft.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab155512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).

Target

  • Function
    Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
  • Tissue specificity
    Widely expressed. Strong expression in liver, brain and prostate.
  • Sequence similarities
    Contains 1 CRAL-TRIO domain.
    Contains 1 GOLD domain.
  • Developmental stage
    Low expression in fetal tissues.
  • Cellular localization
    Cytoplasm. Nucleus. Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha tocopherol associated protein antibody
    • Alpha-tocopherol-associated protein antibody
    • C22orf6 antibody
    • HGNC:10699 antibody
    • hTAP antibody
    • KIAA1186 antibody
    • KIAA1658 antibody
    • MGC65053 antibody
    • S14L2_HUMAN antibody
    • SEC14 like 2 antibody
    • SEC14 like protein 2 antibody
    • SEC14-like protein 2 antibody
    • Sec14l2 antibody
    • SPF antibody
    • Squalene transfer protein antibody
    • Supernatant protein factor antibody
    • TAP antibody
    • TAP1 antibody
    • Tocopherol associated protein antibody
    see all

Images

  • Anti-SEC14L2 antibody (ab155512) at 1/500 dilution + U87-MG whole cell lysate at 30 µg

    Predicted band size: 45 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded H1299 xenograft labeling SEC14L2 with ab155512 at 1/100 dilution.

References

ab155512 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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