Overview

  • Product name

    Anti-SEC14L2/TAP antibody [EPR8612]
    See all SEC14L2/TAP primary antibodies
  • Description

    Rabbit monoclonal [EPR8612] to SEC14L2/TAP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IF, IPmore details
    Unsuitable for: Flow Cyt
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human SEC14L2/TAP aa 250-350. The exact sequence is proprietary.
    Database link: O76054

  • Positive control

    • Fetal liver, fetal brain, U87-MG, and PC-3 lysates; Human brain and Human liver tissues
  • General notes

    Product previously known as Anti-SEC14L2 antibody [EPR8612].

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR8612
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab137013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 46 kDa.
IHC-P 1/250 - 1/500.
ICC/IF 1/250 - 1/500.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt.
  • Target

    • Function

      Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
    • Tissue specificity

      Widely expressed. Strong expression in liver, brain and prostate.
    • Sequence similarities

      Contains 1 CRAL-TRIO domain.
      Contains 1 GOLD domain.
    • Developmental stage

      Low expression in fetal tissues.
    • Cellular localization

      Cytoplasm. Nucleus. Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
    • Information by UniProt
    • Database links

    • Alternative names

      • Alpha tocopherol associated protein antibody
      • Alpha-tocopherol-associated protein antibody
      • C22orf6 antibody
      • HGNC:10699 antibody
      • hTAP antibody
      • KIAA1186 antibody
      • KIAA1658 antibody
      • MGC65053 antibody
      • S14L2_HUMAN antibody
      • SEC14 like 2 antibody
      • SEC14 like protein 2 antibody
      • SEC14-like protein 2 antibody
      • Sec14l2 antibody
      • SPF antibody
      • Squalene transfer protein antibody
      • Supernatant protein factor antibody
      • TAP antibody
      • TAP1 antibody
      • Tocopherol associated protein antibody
      see all

    Images

    • All lanes : Anti-SEC14L2/TAP antibody [EPR8612] (ab137013) at 1/1000 dilution

      Lane 1 : Fetal liver lysate
      Lane 2 : Fetal brain lysate
      Lane 3 : U87-MG lysate
      Lane 4 : PC-3 lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 46 kDa

    • Immunohistochemical analysis of paraffin-embedded Human brain tissue labelling SEC14L2/TAP with ab137013 at 1/250 dilution.

    • Immunohistochemical analysis of paraffin-embedded Human liver tissue labelling SEC14L2/TAP with ab137013 at 1/250 dilution.

    References

    This product has been referenced in:

    • Costa R  et al. SEC14L2, a lipid-binding protein, regulates HCV replication in culture with inter- and intra-genotype variations. J Hepatol N/A:N/A (2018). Read more (PubMed: 30472319) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab137013.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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