Key features and details
- Rabbit polyclonal to Sec24C
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Sec24C antibody
See all Sec24C primary antibodies
DescriptionRabbit polyclonal to Sec24C
Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
Species reactivityReacts with: Human
- U 251 MG cells; RT 4, U 251 MG, Human liver and tonsil lysates; Human stomach tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab122633 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml.|
FunctionComponent of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Sequence similaritiesBelongs to the SEC23/SEC24 family. SEC24 subfamily.
Cellular localizationCytoplasm. Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane.
- Information by UniProt
- Protein transport protein Sec24C antibody
- SC 24C antibody
- SC24 C antibody
All lanes : Anti-Sec24C antibody (ab122633) at 1/250 dilution
Lane 1 : RT 4 lysate
Lane 2 : U 251 MG lysate
Lane 3 : Human plasma lysate
Lane 4 : Human Liver lysate
Lane 5 : Human Tonsil lysate
Developed using the ECL technique.
ab122633 at 1/200 dilution staining Sec24C in paraffin-embedded Human stomach tissue by Immunohistochemistry.
ab122633 at 4 µg/ml staining SEC24C in PFA/Triton X-100 fixed/permeabilized U 251 MG cells by Immunofluorescence (green).
ab122633 has been referenced in 1 publication.
- Wang B et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest 128:3319-3332 (2018). PubMed: 29939162