Product nameAnti-SEC61A antibody
See all SEC61A primary antibodies
DescriptionRabbit polyclonal to SEC61A
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Dog, Human, Pig
Predicted to work with: Cow
- Pig microsomes
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Our Abpromise guarantee covers the use of ab15575 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000. Detects a band of approximately 38 kDa (predicted molecular weight: 52 kDa).
Detects a band of approximately 38 kDa representing sec61 alpha from pig microsomes.
|ICC/IF||1/1000. PubMed: 18784250|
FunctionPlays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.
Sequence similaritiesBelongs to the secY/SEC61-alpha family.
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
- chunp6898 antibody
- fb62c11 antibody
- HSEC61 antibody
This product has been referenced in:
- Taverna E et al. Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells. Sci Rep 6:21206 (2016). IF . Read more (PubMed: 26879757) »
- Buck TM et al. The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel. J Biol Chem 288:18366-80 (2013). WB . Read more (PubMed: 23645669) »