Overview

  • Product name

  • Description

    Rabbit polyclonal to SECISBP2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human SECISBP2 aa 270-854 (C terminal).
    Database link: Q96T21

  • Positive control

    • IF; HeLa cells. WB: MCF7, BT-474, HeLa, 293T and mouse thymus extract. IHC-P: Human liver injury tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab210791 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 95 kDa.
IF 1/50 - 1/100.

Target

  • Function

    Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
  • Tissue specificity

    Expressed at high levels in testis.
  • Involvement in disease

    Defects in SECISBP2 are a cause of abnormal thyroid hormone metabolism (ATHYHM) [MIM:609698]. This phenotype is associated with a reduction in type II iodothyronine deiodinase activity.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp686C09169 antibody
    • OTTHUMP00000064929 antibody
    • OTTHUMP00000064930 antibody
    • OTTHUMP00000064931 antibody
    • OTTHUMP00000064932 antibody
    • RP11 89K14.1 antibody
    • SBP 2 antibody
    • SBP2 antibody
    • SEBP2_HUMAN antibody
    • SECIS binding protein 2 antibody
    • SECIS-binding protein 2 antibody
    • SECISBP 2 antibody
    • SECISBP2 antibody
    • Selenocysteine insertion sequence binding protein 2 antibody
    • Selenocysteine insertion sequence-binding protein 2 antibody
    see all

Images

  • All lanes : Anti-SECISBP2 antibody (ab210791) at 1/500 dilution

    Lane 1 : MCF7 extract
    Lane 2 : BT-474 extract
    Lane 3 : HeLa extract
    Lane 4 : 293T extract
    Lane 5 : Mouse thymus

    Predicted band size: 95 kDa

  • Immunohistochemical analysis of human colon carcinoma tissue paraffin-embedded sections labeling SECISBP2 with ab210791 at a 1/200 dilution.

  • Immunofluorescent analysis of HeLa cells labeling SECISBP2 with ab210791 at 1/50 dilution. 

  • Immunohistochemical analysis of human liver injury tissue paraffin-embedded sections labeling SECISBP2 with ab210791 at a 1/200 dilution.

References

ab210791 has not yet been referenced specifically in any publications.

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