Key features and details
- Rabbit polyclonal to SECISBP2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-SECISBP2 antibody
See all SECISBP2 primary antibodies
DescriptionRabbit polyclonal to SECISBP2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment corresponding to Human SECISBP2 aa 270-854 (C terminal).
Database link: Q96T21
- IF; HeLa cells. WB: MCF7, BT-474, HeLa, 293T and mouse thymus extract. IHC-P: Human liver injury tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Purine and pyrimidine synthesis
Our Abpromise guarantee covers the use of ab210791 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
|WB||1/500 - 1/2000. Predicted molecular weight: 95 kDa.|
|IF||1/50 - 1/100.|
FunctionBinds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
Tissue specificityExpressed at high levels in testis.
Involvement in diseaseDefects in SECISBP2 are a cause of abnormal thyroid hormone metabolism (ATHYHM) [MIM:609698]. This phenotype is associated with a reduction in type II iodothyronine deiodinase activity.
- Information by UniProt
- DKFZp686C09169 antibody
- OTTHUMP00000064929 antibody
- OTTHUMP00000064930 antibody
All lanes : Anti-SECISBP2 antibody (ab210791) at 1/500 dilution
Lane 1 : MCF7 extract
Lane 2 : BT-474 extract
Lane 3 : HeLa extract
Lane 4 : 293T extract
Lane 5 : Mouse thymus
Predicted band size: 95 kDa
Immunohistochemical analysis of human colon carcinoma tissue paraffin-embedded sections labeling SECISBP2 with ab210791 at a 1/200 dilution.
Immunofluorescent analysis of HeLa cells labeling SECISBP2 with ab210791 at 1/50 dilution.
Immunohistochemical analysis of human liver injury tissue paraffin-embedded sections labeling SECISBP2 with ab210791 at a 1/200 dilution.
ab210791 has not yet been referenced specifically in any publications.