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Anti-Selenium Binding Protein 1/SBP antibody (ab180782)

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Western blot - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
  • Immunocytochemistry/ Immunofluorescence - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)

Key features and details

  • Rabbit polyclonal to Selenium Binding Protein 1/SBP
  • Suitable for: IHC-P, WB, ICC/IF
  • Reacts with: Rat, Human
  • Isotype: IgG

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Overview

  • Product name

    Anti-Selenium Binding Protein 1/SBP antibody
    See all Selenium Binding Protein 1/SBP primary antibodies
  • Description

    Rabbit polyclonal to Selenium Binding Protein 1/SBP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Cow, Orangutan
  • Immunogen

    Recombinant fragment corresponding to Human Selenium Binding Protein 1/SBP (C terminal).
    Database link: Q13228

  • Positive control

    • 721_B cell lysate
  • General notes

    Previously labelled as Selenium Binding Protein 1. 

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other
    • Signal Transduction
    • Metabolism
    • Vitamins / Minerals
    • Cancer
    • Oncoproteins/suppressors
    • Tumor suppressors
    • Other
    • Metabolism
    • Pathways and Processes
    • Cofactors, Vitamins / minerals
    • Vitamins / minerals

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab180782 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
1/50 - 1/200.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

WB
1/500 - 1/2000. Predicted molecular weight: 52 kDa.
ICC/IF
Use at an assay dependent concentration.
Notes
IHC-P
1/50 - 1/200.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

WB
1/500 - 1/2000. Predicted molecular weight: 52 kDa.
ICC/IF
Use at an assay dependent concentration.

Target

  • Function

    Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
  • Tissue specificity

    Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
  • Sequence similarities

    Belongs to the selenium-binding protein family.
  • Post-translational
    modifications

    Phosphorylated.
    The N-terminus is blocked.
  • Cellular localization

    Nucleus. Cytoplasm > cytosol. Membrane. May associate with Golgi membrane. May associate with the membrane of autophagosomes.
  • Target information above from: UniProt accession Q13228 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 510154 Cow
    • Entrez Gene: 8991 Human
    • Entrez Gene: 140927 Rat
    • Omim: 604188 Human
    • SwissProt: Q2KJ32 Cow
    • SwissProt: Q13228 Human
    • SwissProt: Q8VIF7 Rat
    • Unigene: 632460 Human
    • Unigene: 16617 Rat
    see all
  • Alternative names

    • 56 kDa selenium binding protein antibody
    • 56 kDa selenium-binding protein antibody
    • hSBP antibody
    • LPSB antibody
    • SBP antibody
    • SBP1 antibody
    • SBP1_HUMAN antibody
    • SBP56 antibody
    • Selenbp1 antibody
    • Selenbp2 antibody
    • Selenium Binding Protein 1 antibody
    • Selenium binding protein 2 antibody
    • Selenium binding protein1 antibody
    • Selenium-binding protein 1 antibody
    • SELNBP1 antibody
    • SP56 antibody
    see all

Images

  • Western blot - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
    Western blot - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
    Anti-Selenium Binding Protein 1/SBP antibody (ab180782) at 1/500 dilution + 721_B cell lysate

    Predicted band size: 52 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat brain tissue labelling Selenium Binding Protein 1/SBP with ab180782 at 1/200. Magnification: 200x.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human thyroid cancer tissue labelling Selenium Binding Protein 1/SBP with ab180782 at 1/200. Magnification: 400x.

  • Immunocytochemistry/ Immunofluorescence - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
    Immunocytochemistry/ Immunofluorescence - Anti-Selenium Binding Protein 1/SBP antibody (ab180782)
    Immunocytochemistry/Immunofluorescence analysis of HeLa cells using ab180782. Blue DAPI for nuclear staining.

Protocols

  • Immunohistochemistry protocols
  • Immunocytochemistry & immunofluorescence protocols
  • Western blot protocols

Click here to view the general protocols

Datasheets and documents

  • SDS download

  • Datasheet download

    Download

References (0)

Publishing research using ab180782? Please let us know so that we can cite the reference in this datasheet.

ab180782 has not yet been referenced specifically in any publications.

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