Overview

  • Product name

  • Description

    Rabbit polyclonal to SEMA5A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human SEMA5A aa 700-960.
    Database link: Q13591

  • Positive control

    • Mouse brain whole cell lysate.
  • General notes

     This product was previously labelled as Semaphorin 5A

     

Properties

Applications

Our Abpromise guarantee covers the use of ab127002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 121 kDa.

Target

  • Relevance

    Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
  • Cellular localization

    Membrane; single-pass type I membrane protein
  • Database links

  • Alternative names

    • SEMA5A antibody
    • SEMAF antibody
    • Semaphorin F antibody

Images

  • Anti-SEMA5A antibody (ab127002) at 1/1000 dilution + Mouse brain whole cell
    lysate at 50 µg

    Predicted band size: 121 kDa



    5% SDS PAGE

References

ab127002 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127002.
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