Overview

  • Product name

  • Description

    Rabbit polyclonal to Sema6A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Recombinant fragment
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human Sema6A aa 1-100 conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab27882)

  • Positive control

    • This antibody gave a positive signal in SEMA6A Recombinant protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab34818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 µg/ml.

    ELISA: This antibody gave a positive result in ELISA against the immunizing peptide (ab27882).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
    • Sequence similarities

      Belongs to the semaphorin family.
      Contains 1 PSI domain.
      Contains 1 Sema domain.
    • Cellular localization

      Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • HT018 antibody
      • SEM6A_HUMAN antibody
      • SEMA antibody
      • Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A antibody
      • Sema Q antibody
      • Sema VIA antibody
      • SEMA6A 1 antibody
      • Sema6a antibody
      • SEMA6A-1 antibody
      • SEMA6A1 antibody
      • Semaphorin 6A 1 antibody
      • Semaphorin Q antibody
      • Semaphorin VIA antibody
      • Semaphorin-6A antibody
      • Semaphorin-6A-1 antibody
      • SEMAQ antibody
      • VIA antibody
      see all

    Images

    • Anti-Sema6A antibody (ab34818) at 1 µg/ml + SEMA6A Recombinant protein (Abnova) at 0.1 µg

      Secondary
      Rabbit IgG secondary antibody (ab28446) at 1/10000 dilution

      Performed under reducing conditions.

      Observed band size: 39 kDa
      why is the actual band size different from the predicted?



      This antibody detects a Sema6A recombinant protein in Western blot.

    References

    ab34818 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab34818.
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