Overview

  • Product name

    Anti-Semaphorin 4D/CD100 antibody [A8]
    See all Semaphorin 4D/CD100 primary antibodies
  • Description

    Mouse monoclonal [A8] to Semaphorin 4D/CD100
  • Host species

    Mouse
  • Tested applications

    Suitable for: IP, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human Semaphorin 4D/CD100.

  • Positive control

    • Human lymphocytes.
  • General notes

     This product was previously labelled as Semaphorin 4D

     

Properties

Applications

Our Abpromise guarantee covers the use of ab86829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
Flow Cyt Use 0.25µg for 106 cells.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.
  • Tissue specificity

    Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.
  • Sequence similarities

    Belongs to the semaphorin family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 PSI domain.
    Contains 1 Sema domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • A8 antibody
    • BB 18 antibody
    • BB18 antibody
    • CD 100 antibody
    • CD100 antibody
    • CD100 antigen antibody
    • Coll 4 antibody
    • COLL4 antibody
    • Collapsin 4 antibody
    • Collapsin4 antibody
    • GR3 antibody
    • Leukocyte activation antigen CD100 antibody
    • M sema G antibody
    • MSEMA antibody
    • SEM4D_HUMAN antibody
    • Sema 4d antibody
    • Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D antibody
    • Sema H antibody
    • SEMA J antibody
    • Sema4d antibody
    • Semacl 2 antibody
    • Semacl2 antibody
    • SemaH antibody
    • SEMAJ antibody
    • Semaphorin 4D antibody
    • Semaphorin C like 2 antibody
    • Semaphorin H antibody
    • Semaphorin J antibody
    • Semaphorin-4D antibody
    • Semaphorin4D antibody
    • SemaphorinJ antibody
    • Semcl 2 antibody
    • Semcl2 antibody
    see all

Images

  • Cell surface flow cytometric analysis of Semaphorin 4D/CD100 in human lymphocytes using ab86829 at 0.25 ug/106 cells. Shaded histogram represents cells without antibody; green represents isotype control; red represents ab86829. A Goat anti-mouse IgG PE conjugated secondary was used in this test.

References

This product has been referenced in:

  • Hall KT  et al. Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. Proc Natl Acad Sci U S A 93:11780-5 (1996). Read more (PubMed: 8876214) »
See 1 Publication for this product

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