Overview

  • Product name

    Senegenin (Tenuigenin), Anti-infammatory agent
  • Description

    Anti-infammatory agent
  • Biological description

    Anti-inflammatory agent. Inhibits IL-6 and IL-8, TNF-α and interleukin-1β expression. Increases NR2B expression. Shows anti-ischemic, neuroprotective and neuroregenerative effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    2469-34-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lin L  et al. Simultaneous analysis of polygala acid, senegenin and 3,6'-disinapoylsucrose in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study after oral administration. Biomed Chromatogr 28:594-600 (2014). Read more (PubMed: 24222473) »
  • Yu L  et al. Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats. Exp Ther Med 7:821-826 (2014). Read more (PubMed: 24660030) »
  • Xie W  et al. Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats. PLoS One 7:e45575 (2012). Read more (PubMed: 23029109) »

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