Overview

  • Product name

    Anti-SENP8 antibody - N-terminal
    See all SENP8 primary antibodies
  • Description

    Rabbit polyclonal to SENP8 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Monkey
  • Immunogen

    Synthetic peptide, corresponding to a region within N terminal amino acids 1 - 65 of Human SENP8.

  • Positive control

    • 293T, H1299, HeLaS3, HepG2, Molt-4 and Raji whole cell lysates; SW480 xenograft.

Properties

Applications

Our Abpromise guarantee covers the use of ab137439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 24 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
  • Tissue specificity

    Broadly expressed, with highest levels in kidney and pancreas.
  • Sequence similarities

    Belongs to the peptidase C48 family.
  • Information by UniProt
  • Database links

  • Alternative names

    • cysteine 2 antibody
    • DEN 1 antibody
    • DEN1 antibody
    • Deneddylase 1 antibody
    • Deneddylase-1 antibody
    • FKSG8 antibody
    • HsT17512 antibody
    • NEDD 8 specific protease 1 antibody
    • NEDD8 specific protease cysteine 2 antibody
    • NEDD8-specific protease 1 antibody
    • NEDP 1 antibody
    • NEDP1 antibody
    • Protease antibody
    • Protease, cysteine 2 antibody
    • PRSC2 antibody
    • SENP8 antibody
    • SENP8_HUMAN antibody
    • Sentrin / SUMO specific protease SENP 8 antibody
    • Sentrin-specific protease 8 antibody
    • Sentrin/SUMO-specific protease SENP8 antibody
    • SUMO sentrin specific protease family member 8 antibody
    • SUMO/sentrin peptidase family member, NEDD8 specific antibody
    • SUMO/sentrin specific peptidase family member 8 antibody
    see all

Images

  • Anti-SENP8 antibody - N-terminal (ab137439) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size: 24 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of parafin-embedded SW480 xenograft labelling SENP8 with ab137439 at 1/500 dilution.

References

ab137439 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab137439.
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