Overview

  • Product name

  • Description

    Rabbit polyclonal to SEPP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 157-411 of Human SEPP1.

  • Positive control

    • Jurkat and Raji whole cell lysates; Human U87 xenograft tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78% PBS, 20% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab155185 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 43 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
  • Tissue specificity

    Made in the liver and heart and secreted into the plasma. It is also found in the kidney.
  • Sequence similarities

    Belongs to the selenoprotein P family.
  • Post-translational
    modifications

    Phosphorylation sites are present in the extracelllular medium.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Selenoprotein P antibody
    • Selenoprotein P plasma 1 antibody
    • Selp antibody
    • SeP antibody
    • Sepp1 antibody
    • SEPP1_HUMAN antibody
    see all

Images

  • All lanes : Anti-SEPP1 antibody (ab155185) at 1/1000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 43 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded U87 xenograft labeling SEPP1 with ab155185 at 1/500 dilution.

References

This product has been referenced in:

  • Mayer K  et al. Diphthamide affects selenoprotein expression: Diphthamide deficiency reduces selenocysteine incorporation, decreases selenite sensitivity and pre-disposes to oxidative stress. Redox Biol 20:146-156 (2019). Read more (PubMed: 30312900) »
See 1 Publication for this product

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