Anti-SEPT4 antibody (ab9651)
Key features and details
- Rabbit polyclonal to SEPT4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SEPT4 antibody
See all SEPT4 primary antibodies -
Description
Rabbit polyclonal to SEPT4 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human SEPT4 aa 3-14.
Sequence:KRFLEDTTDDGE
(Peptide available asab9652) -
Positive control
- Human lung, kidney and spleen tissue lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab9651 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 32 kDa.
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| Notes |
|---|
|
WB
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 32 kDa. |
Target
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Function
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli. -
Tissue specificity
Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets. -
Sequence similarities
Belongs to the septin family. -
Cellular localization
Cytoplasm. Cytoplasm > cytoskeleton. In platelets, found in areas surrounding alpha-granules and Mitochondrion. Nucleus. While predominantly localized in the mitochondria under resting conditions, isoform ARTS translocates into the nucleus after TGF-beta treatment and apoptosis induction. - Information by UniProt
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Database links
- Entrez Gene: 5414 Human
- Omim: 603696 Human
- SwissProt: O43236 Human
- Unigene: 287518 Human
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Alternative names
- Apoptosis-related protein in the TGF-beta signaling pathway antibody
- ARTS antibody
- Bradeion antibody
see all
Images
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Western blot - Anti-SEPT4 antibody (ab9651)
Western blot analysis of SEPT4 expression in human lung (lane 1), spleen (lane 2), and kidney (lane 3) tissue lysates with anti-SEPT4 at 2 µg /ml.
Western blot analysis of SEPT4 expression in human lung (lane 1), spleen (lane 2), and kidney (lane 3) tissue lysates with anti-SEPT4 at 2 µg /ml.
Datasheets and documents
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Datasheet download
References (0)
ab9651 has not yet been referenced specifically in any publications.
