Overview

  • Product name

    Anti-SERBP1 antibody
  • Description

    Rabbit polyclonal to SERBP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC, WB, ELISA, ICC/IF, IHC (PFA fixed)more details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to C-terminal residues of human SERBP1.

Properties

Applications

Our Abpromise guarantee covers the use of ab55993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC (PFA fixed) Use at an assay dependent concentration.

Target

  • Function

    May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
  • Tissue specificity

    Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
  • Cellular localization

    Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Also found in perinuclear regions.
  • Information by UniProt
  • Database links

  • Alternative names

    • CGI 55 antibody
    • CHD3IP antibody
    • Chromodomain helicase DNA binding protein 3 interacting protein antibody
    • DKFZp564M2423 antibody
    • FLJ90489 antibody
    • HABP4L antibody
    • PAI 1 mRNA binding protein antibody
    • PAI RBP1 antibody
    • PAI-RBP1 antibody
    • PAI1 RNA-binding protein 1 antibody
    • PAIRB_HUMAN antibody
    • PAIRBP1 antibody
    • Plasminogen activator inhibitor 1 RNA binding protein antibody
    • Plasminogen activator inhibitor 1 RNA-binding protein antibody
    • Serbp1 antibody
    • SERPINE1 mRNA binding protein 1 antibody
    • SERPINE1 mRNA-binding protein 1 antibody
    see all

References

This product has been referenced in:

  • Bashour NM & Wray S Progesterone directly and rapidly inhibits GnRH neuronal activity via progesterone receptor membrane component 1. Endocrinology 153:4457-69 (2012). Read more (PubMed: 22822163) »
See 1 Publication for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Immunocytochemistry/ Immunofluorescence
Sample
Mouse Cell (fixed brain slices)
Specification
fixed brain slices
Fixative
Formaldehyde
Permeabilization
Yes - 0.3% Triton-X during blocking step
Blocking step
Normal Goat Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 25°C

Mr. Nicholas Bashour

Verified customer

Submitted Apr 01 2011

Application
Immunohistochemistry (PFA fixed)
Sample
Mouse Tissue sections (uterus)
Specification
uterus

Mr. Nicholas Bashour

Verified customer

Submitted Feb 17 2011

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