Anti-SERCA2 ATPase antibody [2A7-A1] (ab2861)

Mouse monoclonal SERCA2 ATPase antibody [2A7-A1]. Validated in WB, IP, IHC, ICC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Sheep, Rabbit, Guinea pig, Dog, Human, Pig, Xenopus laevis.

Publishing research using ab2861? Please let us know so that we can cite the reference in this datasheet.

ab2861 has been referenced in 58 publications.

  • Wang R  et al. The Cardiotoxicity Induced by Arsenic Trioxide is Alleviated by Salvianolic Acid A via Maintaining Calcium Homeostasis and Inhibiting Endoplasmic Reticulum Stress. Molecules 24:N/A (2019). PubMed: 30717322
  • Zhang Y  et al. LncRNA ZFAS1 as a SERCA2a Inhibitor to Cause Intracellular Ca2+ Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction. Circ Res 122:1354-1368 (2018). PubMed: 29475982
  • Cha HH  et al. Changes in calcium channel proteins according to magnesium sulfate administration in placentas from pregnancies with pre-eclampsia or fetal growth restriction. J Investig Med N/A:N/A (2018). PubMed: 30415221
  • Koivumäki JT  et al. Structural Immaturity of Human iPSC-Derived Cardiomyocytes:In SilicoInvestigation of Effects on Function and Disease Modeling. Front Physiol 9:80 (2018). PubMed: 29467678
  • Chen X  et al. Sorcin ablation plus ß-adrenergic stimulation generate an arrhythmogenic substrate in mouse ventricular myocytes. J Mol Cell Cardiol 114:199-210 (2018). WB ; Mouse . PubMed: 29174767
  • Hilse KE  et al. The Expression of Uncoupling Protein 3 Coincides With the Fatty Acid Oxidation Type of Metabolism in Adult Murine Heart. Front Physiol 9:747 (2018). PubMed: 29988383
  • Guo H  et al. Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKa-regulated autophagy induction in streptozotocin-induced diabetic nephropathy. Sci Rep 7:6852 (2017). PubMed: 28761152
  • Tarazón E  et al. SERCA2a: A potential non-invasive biomarker of cardiac allograft rejection. J Heart Lung Transplant 36:1322-1328 (2017). FM . PubMed: 28750934
  • Sokolina K  et al. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Mol Syst Biol 13:918 (2017). IP . PubMed: 28298427
  • Kalbitz M  et al. Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro. J Immunol 197:2353-61 (2016). PubMed: 27521340
  • Le Page S  et al. Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model. PLoS One 11:e0164066 (2016). WB . PubMed: 27723783
  • Riedl I  et al. AMPK?3 is dispensable for skeletal muscle hypertrophy induced by functional overload. Am J Physiol Endocrinol Metab 310:E461-72 (2016). PubMed: 26758685
  • Zoladz JA  et al. Mechanisms of Attenuation of Pulmonary V'O2 Slow Component in Humans after Prolonged Endurance Training. PLoS One 11:e0154135 (2016). WB . PubMed: 27104346
  • Shinde V  et al. Unfolded protein response-induced dysregulation of calcium homeostasis promotes retinal degeneration in rat models of autosomal dominant retinitis pigmentosa. Cell Death Dis 7:e2085 (2016). WB . PubMed: 26844699
  • Aoyama M  et al. Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly Activated by Cyclic AMP 1/Ras-Related Protein 1 Axis. Circ Heart Fail 9:e002081 (2016). PubMed: 26721911
  • Prathipati P  et al. Ablation of Matrix Metalloproteinase-9 Prevents Cardiomyocytes Contractile Dysfunction in Diabetics. Front Physiol 7:93 (2016). WB . PubMed: 27014091
  • Zaman JA  et al. Post-operative atrial fibrillation is associated with a pre-existing structural and electrical substrate in human right atrial myocardium. Int J Cardiol 220:580-8 (2016). PubMed: 27390994
  • Nandi SS  et al. Lack of miR-133a Decreases Contractility of Diabetic Hearts: A Role for Novel Cross Talk Between Tyrosine Aminotransferase and Tyrosine Hydroxylase. Diabetes 65:3075-90 (2016). PubMed: 27411382
  • Liu J  et al. Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells. Front Physiol 6:69 (2015). PubMed: 25806000
  • Nonaka M  et al. Stage-dependent benefits and risks of pimobendan in mice with genetic dilated cardiomyopathy and progressive heart failure. Br J Pharmacol 172:2369-82 (2015). PubMed: 25560565
  • Li Y  et al. Short-term vagal nerve stimulation improves left ventricular function following chronic heart failure in rats. Mol Med Rep 12:1709-16 (2015). WB . PubMed: 25873055
  • Chen G  et al. Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circ Arrhythm Electrophysiol 8:193-202 (2015). PubMed: 25504561
  • Moreira-Gonçalves D  et al. Intermittent cardiac overload results in adaptive hypertrophy and provides protection against left ventricular acute pressure overload insult. J Physiol 593:3885-97 (2015). PubMed: 26010517
  • Olsson K  et al. Intracellular Ca(2+)-handling differs markedly between intact human muscle fibers and myotubes. Skelet Muscle 5:26 (2015). WB, ICC/IF ; Human . PubMed: 26301072
  • Branco AF  et al. Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype. PLoS One 10:e0129303 (2015). PubMed: 26121149
  • Giorgi C  et al. p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner. Proc Natl Acad Sci U S A 112:1779-84 (2015). WB . PubMed: 25624484
  • Gruber SJ  et al. Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells. J Biomol Screen 19:215-22 (2014). WB ; Human . PubMed: 24436077
  • Traister A  et al. Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function. Nat Commun 5:4533 (2014). Human . PubMed: 25208486
  • Zhang D  et al. Hailey-Hailey disease: investigation of a possible compensatory SERCA2 up-regulation and analysis of SPCA1, p63, and IRF6 expression. Arch Dermatol Res N/A:N/A (2014). PubMed: 25256005
  • Ramos SV  et al. Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb. Physiol Rep 2:N/A (2014). WB ; Rat . PubMed: 25318747
  • Benech JC  et al. Diabetes increases stiffness of live cardiomyocytes measured by atomic force microscopy nanoindentation. Am J Physiol Cell Physiol 307:C910-9 (2014). PubMed: 25163520
  • Morgan KY & Black LD Mimicking isovolumic contraction with combined electromechanical stimulation improves the development of engineered cardiac constructs. Tissue Eng Part A 20:1654-67 (2014). PubMed: 24410342
  • Chow MZ  et al. Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell-derived ventricular cardiomyocytes: insights for driven maturation and hypertrophic growth. Stem Cells Dev 22:2678-90 (2013). PubMed: 23656529
  • O-Uchi J  et al. Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts. Am J Physiol Heart Circ Physiol 305:H1736-51 (2013). PubMed: 24124188
  • Jeyaraj D  et al. Ionic bases for electrical remodeling of the canine cardiac ventricle. Am J Physiol Heart Circ Physiol 305:H410-9 (2013). PubMed: 23709598
  • Christoforou N  et al. Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. PLoS One 8:e65963 (2013). PubMed: 23785459
  • Schulz EM  et al. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. J Biol Chem 288:28925-35 (2013). WB ; Mouse . PubMed: 23960072
  • Manrique C  et al. Obesity and insulin resistance induce early development of diastolic dysfunction in young female mice fed a Western diet. Endocrinology 154:3632-42 (2013). WB ; Mouse . PubMed: 23885014
  • Huang Y  et al. Sarcoplasmic phospholamban protein is involved in the mechanisms of postresuscitation myocardial dysfunction and the cardioprotective effect of nitrite during resuscitation. PLoS One 8:e82552 (2013). WB ; Rat . PubMed: 24386101
  • Hydock DS  et al. Exercise preconditioning provides long-term protection against early chronic doxorubicin cardiotoxicity. Integr Cancer Ther 10:47-57 (2011). PubMed: 21382960
  • Sjåland C  et al. Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle. J Physiol 589:6139-55 (2011). PubMed: 21946846
  • Harris RL  et al. Tail muscle parvalbumin content is decreased in chronic sacral spinal cord injured rats with spasticity. Exp Physiol 96:1311-20 (2011). WB ; Rat . PubMed: 21930674
  • Ward ML  et al. Non-steady-state calcium handling in failing hearts from the spontaneously hypertensive rat. Pflugers Arch 460:991-1001 (2010). IHC-Fr ; Rat . PubMed: 20857306
  • Jeong MY  et al. AFos inhibits phenylephrine-mediated contractile dysfunction by altering phospholamban phosphorylation. Am J Physiol Heart Circ Physiol 298:H1719-26 (2010). PubMed: 20363890
  • Heiny JA  et al. The nicotinic acetylcholine receptor and the Na,K-ATPase alpha2 isoform interact to regulate membrane electrogenesis in skeletal muscle. J Biol Chem 285:28614-26 (2010). PubMed: 20595385
  • Hougen K  et al. Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice. Am J Physiol Heart Circ Physiol 299:H1671-8 (2010). PubMed: 20802136
  • Mak S  et al. Differential expression of genes in the calcium-signaling pathway underlies lesion development in the LDb mouse model of atherosclerosis. Atherosclerosis 213:40-51 (2010). PubMed: 20667539
  • Wang YY  et al. Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy. Cardiovasc Res 87:636-46 (2010). PubMed: 20453157
  • Adinolfi E  et al. Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis. J Biol Chem 284:10120-8 (2009). WB ; Human . PubMed: 19204004
  • Liu J  et al. Facilitated maturation of Ca2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression. Am J Physiol Cell Physiol 297:C152-9 (2009). PubMed: 19357236
  • Moshal KS  et al. Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia. Am J Physiol Heart Circ Physiol 295:H890-7 (2008). PubMed: 18567713
  • Gallo M  et al. Adaptive responses to creatine loading and exercise in fast-twitch rat skeletal muscle. Am J Physiol Regul Integr Comp Physiol 294:R1319-28 (2008). PubMed: 18216140
  • Sathish V  et al. Regulation of sarcoplasmic reticulum Ca2+ reuptake in porcine airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 294:L787-96 (2008). PubMed: 18245264
  • Bencsik P  et al. Cardiac capsaicin-sensitive sensory nerves regulate myocardial relaxation via S-nitrosylation of SERCA: role of peroxynitrite. Br J Pharmacol 153:488-96 (2008). PubMed: 18037908
  • Liu CG  et al. 17Beta-oestradiol regulates the expression of Na+/K+-ATPase beta1-subunit, sarcoplasmic reticulum Ca2+-ATPase and carbonic anhydrase iv in H9C2 cells. Clin Exp Pharmacol Physiol 34:998-1004 (2007). PubMed: 17714085
  • Liu J  et al. Functional sarcoplasmic reticulum for calcium handling of human embryonic stem cell-derived cardiomyocytes: insights for driven maturation. Stem Cells 25:3038-44 (2007). WB ; Human . PubMed: 17872499
  • Timolati F  et al. Neuregulin-1 beta attenuates doxorubicin-induced alterations of excitation-contraction coupling and reduces oxidative stress in adult rat cardiomyocytes. J Mol Cell Cardiol 41:845-54 (2006). PubMed: 17005195
  • Chen K  et al. Alpha interferon potently enhances the anti-human immunodeficiency virus type 1 activity of APOBEC3G in resting primary CD4 T cells. J Virol 80:7645-57 (2006). WB ; Human . PubMed: 16840343

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