Question (14733) | Anti-SERCA2 ATPase antibody (ab3625)

Go to datasheet (ab3625)

Question

I need a SERCA2 antibody (which recognizes SERCA2B) for Xenopus laevis. None of your epitopes are available so I cannot evaluate your selection. I have attatched to this e-mail the probable amino acid sequence for this protein in Xenopus and am interested to hear your thoughts on potential antibody choices.

Answer

Thank you for your enquiry. Regarding ab2817 and ab2861: These monoclonal antibodies have not been epitope mapped, therefore the epitope could be anywhere along the full length of the protein. I did an alignment of Human SERCA2 with the Xenopus SERCA2 sequence you attached to your email, and they are 92% homologous. I am not sure if this information helps you in your decision, but I thought I would let you know. I am still looking into ab3625 to see if I can uncover more information about the peptide that was used to produce this antibody. Once I find anything more, I will let you know. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

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