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    serinc2-antibody-ab134312.pdf

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Signal Transduction Metabolism Amino Acids
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Anti-SERINC2 antibody (ab134312)

  • Datasheet
Submit a review Submit a question References (2)

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Find out more.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SERINC2 antibody (ab134312)
  • Western blot - Anti-SERINC2 antibody (ab134312)
  • Immunocytochemistry/ Immunofluorescence - Anti-SERINC2 antibody (ab134312)

Key features and details

  • Rabbit polyclonal to SERINC2
  • Suitable for: WB, IHC-P, ICC/IF
  • Reacts with: Mouse, Human
  • Isotype: IgG

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Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-SERINC2 antibody
  • Description

    Rabbit polyclonal to SERINC2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from the C terminus of Human SERINC2.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol

    PBS without Mg2+ and Ca2+.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Metabolism
    • Amino Acids
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Amino acid metabolism

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Positive Controls

    • HeLa membrane extract lysate (ab29547)

Applications

Our Abpromise guarantee covers the use of ab134312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 51 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF 1/100 - 1/500.

Target

  • Target information above from: UniProt accession Q96SA4 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 347735 Human
    • Entrez Gene: 230779 Mouse
    • Entrez Gene: 313057 Rat
    • Omim: 614549 Human
    • SwissProt: Q96SA4 Human
    • SwissProt: Q8K0E7 Mouse
    • Unigene: 270655 Human
    • Unigene: 45132 Mouse
    • Unigene: 144273 Rat
    see all
  • Alternative names

    • AW121759 antibody
    • FKSG84 antibody
    • MGC116219 antibody
    • MGC90340 antibody
    • PRO0899 antibody
    • RP23 12J1.7 antibody
    • SERC2_HUMAN antibody
    • Serinc2 antibody
    • Serine incorporator 2 antibody
    • TDE2 antibody
    • TDE2L antibody
    • Tumor differentially expressed 2 like antibody
    • Tumor differentially expressed gene 2 antibody
    • Tumor differentially expressed protein 2 antibody
    • Tumor differentially expressed protein 2-like antibody
    • UNQ263/PRO300 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SERINC2 antibody (ab134312)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SERINC2 antibody (ab134312)
    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin (epidermis) tissue labelling SERINC2 with ab134312 at 5 µg/ml, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Western blot - Anti-SERINC2 antibody (ab134312)
    Western blot - Anti-SERINC2 antibody (ab134312)
    All lanes : Anti-SERINC2 antibody (ab134312) at 1/500 dilution

    Lane 1 : HeLa cell extracts
    Lane 2 : HeLa cell extracts with immunising peptide

    Predicted band size: 51 kDa

  • Immunocytochemistry/ Immunofluorescence - Anti-SERINC2 antibody (ab134312)
    Immunocytochemistry/ Immunofluorescence - Anti-SERINC2 antibody (ab134312)
    Immunofluorescent analysis of NIH-3T3 cells labelling SERINC2 with ab134312 at 1/100 dilution. Right image is treated with the immunising peptide.

Protocols

  • Immunohistochemistry protocols
  • Immunocytochemistry & immunofluorescence protocols
  • Western blot protocols

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (2)

    Publishing research using ab134312? Please let us know so that we can cite the reference in this datasheet.

    ab134312 has been referenced in 2 publications.

    • Zeng Y  et al. SERINC2-knockdown inhibits proliferation, migration and invasion in lung adenocarcinoma. Oncol Lett 16:5916-5922 (2018). PubMed: 30405754
    • Mather Q  et al. A novel protein expression signature differentiates benign lipomas from well-differentiated liposarcomas. Mol Clin Oncol 7:315-321 (2017). PubMed: 28781809

    Customer reviews and Q&As

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