Anti-Serotonin transporter antibody (ab102048)


  • Product name
    Anti-Serotonin transporter antibody
    See all Serotonin transporter primary antibodies
  • Description
    Rabbit polyclonal to Serotonin transporter
  • Host species
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-630 of Human Serotonin transporter (AAH69484.1).

  • Positive control
    • Mouse lung lysate. Transfected 293T cell line.



Our Abpromise guarantee covers the use of ab102048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 71 kDa.


  • Function
    Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
  • Tissue specificity
    Expressed in platelets (at protein level).
  • Sequence similarities
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
  • Post-translational
    Glycosylated; modification with sialylated N-glycans is a requirement for transporters to associate with each other and to function as homooligomeric forms.
    Phosphorylated at Ser-611, Thr-613 and Thr-616.
  • Cellular localization
    Cell membrane. Endomembrane system. Endosome membrane. Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 HTT antibody
    • 5 HTTLPR antibody
    • 5 hydroxytryptamine (serotonin) transporter antibody
    • 5 hydroxytryptamine transporter antibody
    • 5HT transporter antibody
    • 5HTT antibody
    • hSERT antibody
    • HTT antibody
    • Na+/Cl- dependent serotonin transporter antibody
    • OCD1 antibody
    • SC6A4_HUMAN antibody
    • Serotonin transporter 1 antibody
    • SERT antibody
    • SERT1 antibody
    • Slc6a4 antibody
    • Sodium dependent serotonin transporter antibody
    • Sodium-dependent serotonin transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter) member 4 antibody
    • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody
    • Solute carrier family 6 member 4 antibody
    see all


  • Anti-Serotonin transporter antibody (ab102048) at 1/500 dilution + Mouse lung tissue lysate at 50 µg

    Developed using the ECL technique.

    Predicted band size: 71 kDa

  • All lanes : Anti-Serotonin transporter antibody (ab102048) at 1/500 dilution

    Lane 1 : Serotonin transporter transfected lysate from 293T cell line
    Lane 2 : Non transfected lysate from 293T cell line

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 71 kDa
    Observed band size: 70.3 kDa (why is the actual band size different from the predicted?)


ab102048 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Abcam has not validated the combination of species/application used in this Abreview.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Human Tissue sections (hct-116)
Antigen retrieval step
Yes - 0.1% TRITON IN PBS
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 0.5% · Temperature: R.T°C

Abcam user community

Verified customer

Submitted Nov 11 2016

Thanks for your enquiry.

I have looked into this question and it appears SERT is expressed in platelets. Perhaps this explains why you do not detect SERT in your macrophage and why samples that are found to express SERT are tissue extracts co...

Read More

As long as the species and application are tested, you will get our Abpromise grantee over 180 days. that means in case the replacement doesn't work either, we'll refund you if you wish.

Please let me know about the alternative antibody of yo...

Read More

Thank you for taking time to complete our questionnaire and for contacting us. I am sorry to hear this antibody is not providing satisfactory results.

The details provided will enable us to investigate this case and will provide us with vita...

Read More

Thank you for contacting us.

I am sorry to hear you are experiencing difficulties with one of our products. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

I a...

Read More

Thank you for your reply.

The images show different band sizes since the samples are different. One image shows a band at 75kda (as predicted). This image was generated with endogenous protein from mouse lung tissue lysate.

The othe...

Read More

Thank you for your inquiry.

We have one antibody that is tested and guaranteed for WB and human and mouse samples:

ab102048 (or use the following:

Read More

Merci pour ces précisions.

Une suggestion que je n'ai pas mentionnée dans mon précédent email est d'essayer d'utiliser 5% de BSA comme agent bloquant à la place du lait. Pour certains anticorps la BSA permet...

Read More

Merci de nous avoir contactés.

A notre connaissance, la réactivité contre les bivalves n'a pas encore été testée avec l'anticorps ab102048. Toutes les informations sur les cross-réactivit&eacut...

Read More


Sign up