Anti-SerpinB2/PAI-2 antibody (ab137588)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-SerpinB2/PAI-2 antibody
See all SerpinB2/PAI-2 primary antibodies -
Description
Rabbit polyclonal to SerpinB2/PAI-2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment corresponding to Human SerpinB2/PAI-2 aa 78-408.
Database link: P05120 -
Positive control
- WB: Human A431 and mouse JC whole cell lysates. IHC-P: Human NCIN87 xenograft tissue.
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General notes
Previously labelled as SerpinB2.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% CMIT/MIT 3:1
Constituents: PBS, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab137588 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 47 kDa. | |
| IHC-P | 1/100 - 1/1000. |
Target
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Function
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. -
Sequence similarities
Belongs to the serpin family. Ov-serpin subfamily. -
Post-translational
modificationsThe signal sequence is not cleaved. -
Cellular localization
Cytoplasm. Secreted > extracellular space. - Information by UniProt
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Database links
- Entrez Gene: 5055 Human
- Entrez Gene: 18788 Mouse
- Omim: 173390 Human
- SwissProt: P05120 Human
- SwissProt: P12388 Mouse
- Unigene: 594481 Human
- Unigene: 271870 Mouse
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Alternative names
- HsT1201 antibody
- Monocyte Arg serpin antibody
- Monocyte Arg-serpin antibody
see all
Images
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Western blot - Anti-SerpinB2/PAI-2 antibody (ab137588)Anti-SerpinB2/PAI-2 antibody (ab137588) at 1/1000 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 47 kDa
10% SDS PAGE -
Western blot - Anti-SerpinB2/PAI-2 antibody (ab137588)Anti-SerpinB2/PAI-2 antibody (ab137588) at 1/1000 dilution + JC whole cell lysate at 30 µg
Predicted band size: 47 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SerpinB2/PAI-2 antibody (ab137588)Immunohistochemical analysis of paraffin embedded human NCIN87 xenograft tissue labeling SerpinB2/PAI-2 with ab137588 at 1/500 dilution.
References
This product has been referenced in:
- Lee JA et al. SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation. PLoS One 10:e0130136 (2015). competitive binding assays ; Mouse . Read more (PubMed: 26083412) »
