Overview

  • Product name

    Anti-SerpinB2/PAI-2 antibody
    See all SerpinB2/PAI-2 primary antibodies
  • Description

    Rabbit polyclonal to SerpinB2/PAI-2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SerpinB2/PAI-2 aa 175-298.
    Sequence:

    TQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRV NSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIAD VSTGLELLESEITYDKLNKWTSKD


    Database link: P05120

  • Positive control

    • IHC-P: Human esophagus tissue.
  • General notes

    Previously labelled as SerpinB2. 

Properties

Applications

Our Abpromise guarantee covers the use of ab223697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
  • Sequence similarities

    Belongs to the serpin family. Ov-serpin subfamily.
  • Post-translational
    modifications

    The signal sequence is not cleaved.
  • Cellular localization

    Cytoplasm. Secreted > extracellular space.
  • Information by UniProt
  • Database links

  • Alternative names

    • HsT1201 antibody
    • Monocyte Arg serpin antibody
    • Monocyte Arg-serpin antibody
    • Monocyte Arginine-serpin antibody
    • Monocyte-derived plasminogen activator inhibitor antibody
    • PAI antibody
    • PAI-2 antibody
    • PAI2 antibody
    • PAI2_HUMAN antibody
    • Placental plasminogen activator inhibitor antibody
    • PLANH2 antibody
    • Plasminogen activator inhibitor 2 antibody
    • plasminogen activator inhibitor, type 2 antibody
    • plasminogen activator inhibitor, type II (arginine-serpin) antibody
    • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 antibody
    • Serpin B2 antibody
    • serpin peptidase inhibitor, clade B (ovalbumin), member 2 antibody
    • Serpinb2 antibody
    • Urokinase inhibitor antibody
    see all

Images

  • Paraffin-embedded human esophagus tissue stained for SerpinB2/PAI-2 using ab223697 at 1/500 dilution in immunohistochemical analysis.

References

ab223697 has not yet been referenced specifically in any publications.

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