Anti-SERPINE2/PN-1 antibody (ab75348)
Key features and details
- Rabbit polyclonal to SERPINE2/PN-1
- Suitable for: ELISA, WB, IHC
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-SERPINE2/PN-1 antibody
See all SERPINE2/PN-1 primary antibodies -
Description
Rabbit polyclonal to SERPINE2/PN-1 -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, WB, IHCmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab75348 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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WB |
1/200 - 1/2000. Predicted molecular weight: 44 kDa.
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IHC |
1/50 - 1/500.
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Notes |
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ELISA
Use at an assay dependent concentration. |
WB
1/200 - 1/2000. Predicted molecular weight: 44 kDa. |
IHC
1/50 - 1/500. |
Target
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Function
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin. -
Sequence similarities
Belongs to the serpin family. -
Cellular localization
Secreted > extracellular space. - Information by UniProt
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Database links
- Entrez Gene: 5270 Human
- Entrez Gene: 20720 Mouse
- Entrez Gene: 29366 Rat
- Omim: 177010 Human
- SwissProt: P07093 Human
- SwissProt: Q07235 Mouse
- SwissProt: P07092 Rat
- Unigene: 38449 Human
see all -
Alternative names
- GDN antibody
- GDN_HUMAN antibody
- GDNPF antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (3)
ab75348 has been referenced in 3 publications.
- Mao M & Wang W SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma. Mol Med Rep 14:881-7 (2016). PubMed: 27221371
- Li X et al. Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition. Sci Rep 6:37635 (2016). WB ; Mouse . PubMed: 27876880
- Wang K et al. Prognostic significance of SERPINE2 in gastric cancer and its biological function in SGC7901 cells. J Cancer Res Clin Oncol 141:805-12 (2015). PubMed: 25359682