Overview

  • Product name

    Anti-SERPINE2/PN-1 antibody
    See all SERPINE2/PN-1 primary antibodies
  • Description

    Rabbit polyclonal to SERPINE2/PN-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human SERPINE2/PN-1 (C terminal).

  • General notes

    Previously labelled as SERPINE2. 

Properties

Applications

Our Abpromise guarantee covers the use of ab75348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent dilution.
WB 1/200 - 1/2000. Predicted molecular weight: 44 kDa.

Target

  • Function

    Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
  • Sequence similarities

    Belongs to the serpin family.
  • Cellular localization

    Secreted > extracellular space.
  • Information by UniProt
  • Database links

  • Alternative names

    • GDN antibody
    • GDN_HUMAN antibody
    • GDNPF antibody
    • Glia derived nexin antibody
    • Glia-derived nexin antibody
    • Glial derived neurite promoting factor antibody
    • P17 antibody
    • Peptidase inhibitor 7 antibody
    • Pi-7 antibody
    • Plasminogen activator inhibitor type 1, member 2 antibody
    • PN-1 antibody
    • PN1 antibody
    • PNI antibody
    • Protease inhibitor 7 antibody
    • Protease nexin 1 antibody
    • Protease nexin I antibody
    • Serpin E2 antibody
    • Serpin family E member 2 antibody
    • Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 antibody
    • SERPINE 2 antibody
    • Serpine2 antibody
    see all

References

This product has been referenced in:

  • Mao M & Wang W SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma. Mol Med Rep 14:881-7 (2016). Read more (PubMed: 27221371) »
  • Li X  et al. Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition. Sci Rep 6:37635 (2016). WB ; Mouse . Read more (PubMed: 27876880) »
See all 3 Publications for this product

Customer reviews and Q&As

Answer

I am very pleased to hear you would like to test ab77788, ab75348, ab112602 in sELISA.Each code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit 3 AbreviewsforsELISA and include the corresponding code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active. For more information on how to submit an Abreview, please visit the site: https://www.abcam.com/Abreviews.

Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: https://www.abcam.com/collaborationdiscount.

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