Recombinant Anti-SETBP1 antibody [SP312] (ab216603)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Key features and details

Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
Rabbit monoclonal [SP312] to SETBP1
Suitable for: IHC-P
Reacts with: Human

Product name

Anti-SETBP1 antibody [SP312]
See all SETBP1 primary antibodies
Description

Rabbit monoclonal [SP312] to SETBP1
Host species

Rabbit
Tested applications

Suitable for: IHC-Pmore details
Species reactivity

Reacts with: Human
Immunogen

Synthetic peptide within Human SETBP1 aa 1550 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: Q9Y6X0
Positive control
- Human liver, lymph node, HK lymphoma, B cell lymphoma, pancreas, pancreatic adenocarcinoma, urinary bladder, urinary bladder transitional cell carcinoma, colon and colon adenocarcinoma tissues.
General notes

This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
Purity

Protein A/G purified
Purification notes

Purified from TCS by protein A/G.
Clonality

Monoclonal
Clone number

SP312
Isotype

IgG
Research areas

Alternative Versions
- Anti-SETBP1 antibody [SP312] - BSA and Azide free (ab272000)
Isotype control
- Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730)

Our Abpromise guarantee covers the use of ab216603 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
IHC-P		1/100. Boil tissue section in EDTA buffer, pH 8.0 for 10 min followed by cooling at room temperature for 20 min. Primary incubation for 10 minutes at room temperature.

Tissue specificity

Expressed in numerous tissues.
Involvement in disease

Defects in SETBP1 are the cause of Schinzel-Giedion midface retraction syndrome (SGMFS) [MIM:269150]. It is a disorder characterized by severe mental retardation, distinctive facial features, and multiple congenital malformations including skeletal abnormalities, genitourinary and renal malformations, cardiac defects, as well as a higher-than-normal prevalence of tumors, notably neuroepithelial neoplasia.
Sequence similarities

Contains 3 A.T hook DNA-binding domains.
Cellular localization

Nucleus.
Target information above from: UniProt accession Q9Y6X0 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 26040 Human
- Omim: 611060 Human
- SwissProt: Q9Y6X0 Human
- Unigene: 435458 Human
Alternative names
- SEB antibody
- SET binding protein 1 antibody
- SET-binding protein antibody
- SETBP 1 antibody
- SETBP_HUMAN antibody
- Setbp1 antibody
see all

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lymph node tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human HK lymphoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human B cell lymphoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreas tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreatic adenocarcinoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human urinary bladder tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human urinary bladder transitional cell carcinoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human colon tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human colon adenocarcinoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.
Anti-SETBP1 antibody [SP312] (ab216603)

Immunohistochemistry protocols

Click here to view the general protocols

Publishing research using ab216603? Please let us know so that we can cite the reference in this datasheet.

ab216603 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Recombinant Anti-SETBP1 antibody [SP312] (ab216603)

Key features and details

Overview

Product name

Description

Host species

Tested applications

Species reactivity

Immunogen

Positive control

General notes

Properties

Form

Storage instructions

Storage buffer

Purity

Purification notes

Clonality

Clone number

Isotype

Research areas

Associated products

Alternative Versions

Isotype control

Applications

Target

Tissue specificity

Involvement in disease

Sequence similarities

Cellular localization

Database links

Alternative names

Images

Protocols

Datasheets and documents

References (0)

Customer reviews and Q&As