Recombinant
RabMAb

Recombinant Anti-SETBP1 antibody [SP312] (ab216603)

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Overview

  • Product name

    Anti-SETBP1 antibody [SP312]
    See all SETBP1 primary antibodies

  • Description

    Rabbit monoclonal [SP312] to SETBP1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide within Human SETBP1 aa 1550 to the C-terminus (C terminal). The exact sequence is proprietary.
    Database link: Q9Y6X0

  • Positive control

    • Human liver, lymph node, HK lymphoma, B cell lymphoma, pancreas, pancreatic adenocarcinoma, urinary bladder, urinary bladder transitional cell carcinoma, colon and colon adenocarcinoma tissues.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.6
    Preservative: 0.1% Sodium azide
    Constituents: PBS, 1% BSA
  • Concentration information loading...

  • Purity

    Protein A/G purified

  • Purification notes

    Purified from TCS by protein A/G.

  • Clonality

    Monoclonal

  • Clone number

    SP312

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab216603 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.

Boil tissue section in EDTA buffer, pH 8.0 for 10 min followed by cooling at room temperature for 20 min. Primary incubation for 10 minutes at room temperature.

Target

  • Tissue specificity

    Expressed in numerous tissues.

  • Involvement in disease

    Defects in SETBP1 are the cause of Schinzel-Giedion midface retraction syndrome (SGMFS) [MIM:269150]. It is a disorder characterized by severe mental retardation, distinctive facial features, and multiple congenital malformations including skeletal abnormalities, genitourinary and renal malformations, cardiac defects, as well as a higher-than-normal prevalence of tumors, notably neuroepithelial neoplasia.

  • Sequence similarities

    Contains 3 A.T hook DNA-binding domains.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    • Alternative names

      • SEB antibody
      • SET binding protein 1 antibody
      • SET-binding protein antibody
      • SETBP 1 antibody
      • SETBP_HUMAN antibody
      • Setbp1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lymph node tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human HK lymphoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human B cell lymphoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreas tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreatic adenocarcinoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human urinary bladder tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human urinary bladder transitional cell carcinoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human colon tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SETBP1 antibody [SP312] (ab216603)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human colon adenocarcinoma tissue labeling SETBP1 with ab216603 at 1/100 dilution.

    References

    ab216603 has not yet been referenced specifically in any publications.

    Publishing research using ab216603? Please let us know so that we can cite the reference in this datasheet.

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