Anti-Sex Hormone Binding Globulin/SHBG antibody (ab198281)

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Overview

  • Product name

    Anti-Sex Hormone Binding Globulin/SHBG antibody
    See all Sex Hormone Binding Globulin/SHBG primary antibodies

  • Description

    Rabbit polyclonal to Sex Hormone Binding Globulin/SHBG

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat

  • Immunogen

    Synthetic peptide corresponding to Human Sex Hormone Binding Globulin/SHBG (internal sequence). (NP_001031).
    Database link: P04278

  • Positive control

    • Human cervical and ovarian cancer tissues.

  • General notes

    Previously labelled as Sex Hormone Binding Globulin. 

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab198281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.

Target

  • Function

    Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.

  • Tissue specificity

    Isoform 1 and isoform 2 are present in liver and testis.

  • Sequence similarities

    Contains 2 laminin G-like domains.

  • Cellular localization

    Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
  • Information by UniProt

  • Database links

    • Alternative names

      • ABP antibody
      • Androgen binding protein antibody
      • SBP antibody
      • Sex hormone-binding globulin antibody
      • Sex steroid binding protein antibody
      • Sex steroid-binding protein antibody
      • SHBG antibody
      • SHBG_HUMAN antibody
      • TeBG antibody
      • Testis specific androgen binding protein antibody
      • Testis-specific androgen-binding protein antibody
      • Testosterone binding beta globulin antibody
      • Testosterone estradiol binding globulin antibody
      • Testosterone estrogen binding globulin antibody
      • Testosterone-estradiol-binding globulin antibody
      • Testosterone-estrogen-binding globulin antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sex Hormone Binding Globulin/SHBG antibody (ab198281)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sex Hormone Binding Globulin/SHBG antibody (ab198281)

      Immunohistochemical analysis of Paraffin-embedded Human ovarian cancer tissue labeling Sex Hormone Binding Globulin/SHBG with ab198281 at 1/20 dilution

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sex Hormone Binding Globulin/SHBG antibody (ab198281)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sex Hormone Binding Globulin/SHBG antibody (ab198281)

      Immunohistochemical analysis of Paraffin-embedded Human cervical cancer tissue labeling Sex Hormone Binding Globulin/SHBG with ab198281 at 1/20 dilution

    References

    ab198281 has not yet been referenced specifically in any publications.

    Publishing research using ab198281? Please let us know so that we can cite the reference in this datasheet.

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